Zobrazeno 1 - 10
of 2 651
pro vyhledávání: '"t cell immunity"'
Autor:
Dantong Sun, Lipin Tan, Yongbing Chen, Qiang Yuan, Kanqiu Jiang, Yangyang Liu, Yuhang Xue, Jinzhi Zhang, Xianbao Cao, Minzhao Xu, Yang Luo, Zhonghua Xu, Zhonghen Xu, Weihua Xu, Mingjing Shen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background Lung cancer remains one of the most prevalent cancer types worldwide, with a high mortality rate. Upregulation of programmed cell death protein 1 (PD-1) and its ligand (PD-L1) may represent a key mechanism for evading immune surve
Externí odkaz:
https://doaj.org/article/a5c8c51ef27847c69ee69bbe67c23fcd
Autor:
Christopher B. Bullock, Leran Wang, Brian C. Ware, Ngan Wagoner, Ray A. Ohara, Tian-Tian Liu, Pritesh Desai, Bjoern Peters, Kenneth M. Murphy, Scott A. Handley, Thomas E. Morrison, Michael S. Diamond
Publikováno v:
mBio, Vol 15, Iss 12 (2024)
ABSTRACT Ross River virus (RRV) and other alphaviruses cause chronic musculoskeletal syndromes that are associated with viral persistence, which suggests deficits in immune clearance mechanisms, including CD8+ T-cell responses. Here, we used a recomb
Externí odkaz:
https://doaj.org/article/abb30f3dcbfe47739c933318bc3cd7c9
Autor:
Xiang Yu, Jinzhou Ou, Lingzhi Wang, Zhenyuan Li, Yingxin Ren, Lang Xie, Zhian Chen, Junxian Liang, Guodong Shen, Zhaowei Zou, Cuiyin Zhao, Guoxin Li, Yanfeng Hu
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTThe gut microbiota and Short-chain fatty acids (SCFAs) can influence the progression of diseases, yet the role of these factors on gastric cancer (GC) remains uncertain. In this work, the analysis of the gut microbiota composition and SCFA co
Externí odkaz:
https://doaj.org/article/a124bec9d6984669ba78f494c3cc8458
Autor:
Stephan J. Holtkamp, Florian R. Lagoda, Adam Lister, Pradeep Harish, Ulrike Kleymann, Theresa Pesch, Chai Fen Soon, Munir Pirmohamed, Dean Naisbitt, Mark Trautwein
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Polyfunctional T cells programmed to perform activities such as degranulation of lytic enzymes and simultaneous production of multiple cytokines are associated with more effective control of viral infections. Immune responses to recombinant adeno-ass
Externí odkaz:
https://doaj.org/article/c5020e034cff45e69f917a6e10973642
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionChronic myeloid leukemia (CML) is a severe hematological malignancy characterized by BCR-ABL fusion gene. The advent of tyrosine kinase inhibitors (TKIs) targeting BCR-ABL has improved the landscape of CML treatment dramatically. The occu
Externí odkaz:
https://doaj.org/article/db0638201f4d40d898d39914ee179a2f
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/f0cc38eb40cb433394fd530ed80abc44
Autor:
Claire M. Doherty, Paige R. Patterson, Julie A. Emeanuwa, Jessica Belmares Ortega, Barbara A. Fox, David J. Bzik, Eric Y. Denkers
Publikováno v:
mBio, Vol 15, Iss 11 (2024)
ABSTRACT As a model organism in the study of immunity to infection, Toxoplasma gondii has been instrumental in establishing key principles of host anti-microbial defense and its regulation. Here, we employed an attenuated uracil auxotroph strain of T
Externí odkaz:
https://doaj.org/article/e4fc1f9b3a5741efafd95bfc8cb21f30
Autor:
Hayden N. Brochu, Elise Smith, Sangmi Jeong, Michelle Carlson, Scott G. Hansen, Jennifer Tisoncik-Go, Lynn Law, Louis J. Picker, Michael Gale, Xinxia Peng
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT Rhesus cytomegalovirus expressing simian immunodeficiency virus (RhCMV/SIV) vaccines protect ~59% of vaccinated rhesus macaques against repeated limiting-dose intra-rectal exposure with highly pathogenic SIVmac239M, but the exact mechanism r
Externí odkaz:
https://doaj.org/article/a83ca6454d1941198785274780932721
Publikováno v:
Veterinary World, Vol 17, Iss 6, Pp 1413-1422 (2024)
Background and Aim: Staphylococcus aureus, with its diverse virulence factors and immune response evasion mechanisms, presents a formidable challenge as an opportunistic pathogen. Developing an effective vaccine against S. aureus has proven elusive d
Externí odkaz:
https://doaj.org/article/e60d1dc0364e417a8d118f00d8bc7a31
Autor:
José Luis Piñana, Estela Giménez, Lourdes Vázquez, María Ángeles Marcos, Manuel Guerreiro, Rafael Duarte, Ariadna Pérez, Carlos de Miguel, Ildefonso Espigado, Marta González-Vicent, María Suarez-Lledó, Irene García-Cadenas, Rodrigo Martino, Angel Cedillo, Monserrat Rovira, Rafael de la Cámara, David Navarro, Carlos Solano
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 16, Iss 1 (2024)
Background: Cytomegalovirus (CMV) infection is a common complication following allogeneic hematopoietic stem cell transplantation (allo-HSCT) and in patients receiving novel hematological therapies. Its impact on morbidity and mortality necessitates
Externí odkaz:
https://doaj.org/article/93399f1e240b4f2e90dc2769016881f2