Zobrazeno 1 - 10
of 233
pro vyhledávání: '"t(11"'
Autor:
Ziwei Zhou, Erling Chen, Jiqian Jiang, Lei Xue, Lijun Zhu, Xing Hu, Yingqiao Zhu, Changcheng Zheng, Juan Tong
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Introduction: Acute promyelocytic leukemia (APL) is mainly due to the chromosome translocation t(15; 17) (q22; q12), leading to the formation of PML-RARα fusion protein. However, some patients carried rare translocation involving RARα gene, and the
Externí odkaz:
https://doaj.org/article/cf8aa9f34d36426a929aab12132b05a0
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Venetoclax is a selective inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (BCL2), as a targeted therapy for multiple myeloma (MM) patients. It was initially approved by the United States Food and Drug Administration for the treatment of chr
Externí odkaz:
https://doaj.org/article/9c59153d5af146aeb7865719eb56c1fe
Autor:
Olivia Lira-Lara, Moisés Manuel Gallardo-Pérez, Solón Javier Garcés-Eisele, Virginia Adriana Reyes-Núñez, Miguel Antonio López-Trujillo, Miranda Melgar-de-la-Paz, Paola Negrete-Rodríguez, Luis Enrique Hamilton-Avilés, Guillermo Ocaña-Ramm, Max Robles-Nasta, Daniela Sánchez-Bonilla, Juan Carlos Olivares-Gazca, Guillermo José Ruiz-Delgado, Guillermo José Ruiz-Argüelles
Publikováno v:
Iraqi Journal of Hematology, Vol 13, Iss 1, Pp 150-153 (2024)
BACKGROUND: Multiple myeloma (MM) is a hematologic malignancy resulting from clonal proliferation of plasma cells in which significant heterogeneity has been demonstrated, both cytogenetically and molecularly. Translocation (11;14)(q13;q32), involvin
Externí odkaz:
https://doaj.org/article/3278542705a942df95bd2681bf8bf8f2
Autor:
Masaya Iwamuro, Ryuta Takenaka, Koji Miyahara, Shotaro Okanoue, Masao Yoshioka, Chihiro Sakaguchi, Kumiko Yamamoto, Yoshinari Kawai, Tatsuya Toyokawa, Takehiro Tanaka, Motoyuki Otsuka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract The objective of this study was to clarify the long-term prognosis of patients with gastric mucosa-associated lymphoid tissue (MALT) lymphoma with additional copies of MALT1. In this multicenter retrospective study, we enrolled 145 patients
Externí odkaz:
https://doaj.org/article/8548f0d3a9574ebb9b4c691ddb316093
Autor:
Hala T. El-Bassyouni, Engy A. Ashaat, Khaled Hamed, Maha Rashed, Azza E. Abd-Elnaby, Marwa Shehab
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-6 (2024)
Abstract Background The hallmarks of Emanuel syndrome are pre- and postnatal growth retardation, microcephaly, global developmental delay, ear anomalies, and in males, heart, kidney, and genital abnormalities. Results This study describes the atypica
Externí odkaz:
https://doaj.org/article/eda3043060a542e784738f1cd6a26243
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionVenetoclax is a BCL-2 inhibitor with proven efficacy in patients with multiple myeloma (MM) and translocation t(11;14). However, its role in plasma cell leukemia (PCL) remains unclear. Herein, we aimed to report a case of relapsed MM with
Externí odkaz:
https://doaj.org/article/470c774a7af44ec1ad222975166f1030
Autor:
Daan A.R. Castelijn, Gerrit Sijm, Bianca Venniker-Punt, Pino J. Poddighe, Marielle J. Wondergem
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 1443-1450 (2023)
Introduction: Acute promyelocytic leukemia (APL) is characterized by the PML::RARa gene fusion and treatment consists of all-trans retinoic acid (ATRA). Rarely, genetic APL variants have been described which are insensitive to ATRA treatment and are
Externí odkaz:
https://doaj.org/article/3767674746294f78937366942e55047d
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 9, Pp 1423-1427 (2023)
Objective To examine the differences in therapy response and confirm the effective regimen for multiple myeloma (MM) patients with t (11; 14)/CD20- or CD20+, for the selection of transplantation as early treatment. Methods To find the differences in
Externí odkaz:
https://doaj.org/article/95f5501be96243ec862904d8bb2c13b1
Autor:
Kenneth JC Lim, Cameron Wellard, Dipti Talaulikar, Joanne LC Tan, Joanna Loh, Pratheepan Puvanakumar, James A Kuzich, Michelle Ho, Matthew Murphy, Nicole Zeglinas, Michael SY Low, David Routledge, Andrew BM Lim, Simon D Gibbs, Hang Quach, Sue Morgan, Elizabeth Moore, Slavisa Ninkovic
Publikováno v:
eJHaem, Vol 4, Iss 3, Pp 639-646 (2023)
Abstract The prognostic impact of t(11;14) in multiple myeloma (MM) needs to be better understood to inform future treatment decisions. The Australian Lymphoma Leukaemia Group embarked on a retrospective, observational cohort study using real‐world
Externí odkaz:
https://doaj.org/article/cb1202c0223440efb5b3d9e055739c68
Autor:
Yusuke Nakamura, Akihiro Takemasa, Yuki Ohoka, Nobuhiko Tsukada, Azusa Tsukada, Yoshimasa Nakazato, Kinuko Mitani, Akihiko Toyoda, Yasuo Shimizu, Seiji Niho
Publikováno v:
Respiratory Medicine Case Reports, Vol 52, Iss , Pp 102133- (2024)
A 76-year-old woman was diagnosed with mucosa-associated lymphoid tissue (MALT) lymphoma by upper gastrointestinal endoscopy. She underwent further investigation for concomitant bilateral pleural effusions and right pulmonary consolidation. MALT lymp
Externí odkaz:
https://doaj.org/article/89ec86c5f2334ebdb6516a539fbba17d