Zobrazeno 1 - 10
of 2 090
pro vyhledávání: '"systems neuroscience"'
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111409- (2024)
Summary: The endocannabinoid system (ECS), which is composed of endocannabinoids (eCBs), cannabinoid receptors (CBRs), and associated signaling molecules, has been identified within the brain. In neuropathic pain animal models and patients, long-last
Externí odkaz:
https://doaj.org/article/7df630d33bb94eb1b0071dce906fadb6
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111410- (2024)
Summary: Endocannabinoids, signaling through the cannabinoid CB1 receptor (CB1R), regulate several forms of neuronal plasticity. CB1Rs in the developing primary visual cortex (V1) play a key role in the maturation of inhibitory circuits. Although CB1
Externí odkaz:
https://doaj.org/article/edd94abe4446493296ecf9d3615c8385
Autor:
Eric H. Chang
Publikováno v:
Frontiers in Systems Biology, Vol 4 (2024)
Externí odkaz:
https://doaj.org/article/4551710c1bab40498bcb448392becffc
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111152- (2024)
Summary: Exogenous opsins allow for in vivo interrogation of brain circuits at unprecedented temporal and spatial precision. Here, we found that optical fiber laser stimulation at wavelengths of 637, 594, or 473 nm within the cortex of mice lacking e
Externí odkaz:
https://doaj.org/article/0ff14bd728cb44419ca8329b99ded003
Autor:
Xuan Luo, Yanyun Ding, Yi Cao, Zhen Liu, Wenchong Zhang, Shangzhi Zeng, Shuk Han Cheng, Honglin Li, Stephen J. Haggarty, Xin Wang, Jin Zhang, Peng Shi
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110875- (2024)
Summary: In this study, we present an approach to neuropharmacological research by integrating few-shot meta-learning algorithms with brain activity mapping (BAMing) to enhance the discovery of central nervous system (CNS) therapeutics. By utilizing
Externí odkaz:
https://doaj.org/article/278cb6cb166b496e8a1de594942c5c13
Autor:
Monika Pupíková, Pablo Maceira-Elvira, Sylvain Harquel, Patrik Šimko, Traian Popa, Martin Gajdoš, Martin Lamoš, Umberto Nencha, Kristína Mitterová, Adam Šimo, Friedhelm C. Hummel, Irena Rektorová
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37427- (2024)
Aging populations face significant cognitive challenges, particularly in working memory (WM). Transcranial alternating current stimulation (tACS) offer promising avenues for cognitive enhancement, especially when inspired by brain physiology. This st
Externí odkaz:
https://doaj.org/article/1eae6ebcb7a346899e7188d718337ca5
Autor:
Chunyu Pan, Quan Zhang, Yue Zhu, Shengzhou Kong, Juan Liu, Changsheng Zhang, Fei Wang, Xizhe Zhang
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110302- (2024)
Summary: The network approach to characterizing psychopathology departs from traditional latent categorical and dimensional approaches. Causal interplay among symptoms contributed to dynamic psychopathology system. Therefore, analyzing the symptom cl
Externí odkaz:
https://doaj.org/article/6f748c9d960c4104b90ce2734b4ef502
Autor:
Zhichun Chen, Wenming Li, Bo Meng, Chongchong Xu, Yiqi Huang, Guanglu Li, Zhexing Wen, Jun Liu, Zixu Mao
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110243- (2024)
Summary: Many clinical studies indicate a significant decrease of peripheral T cells in Parkinson’s disease (PD). There is currently no mechanistic explanation for this important observation. Here, we found that small extracellular vesicles (sEVs)
Externí odkaz:
https://doaj.org/article/c35365e7e66040f28c0ba8cab076e75b
Autor:
Yali Fu, Zixuan Cao, Ting Ye, Hao Yang, Chenshan Chu, Chao Lei, Yaxian Wen, Zhangyin Cai, Yu Yuan, Xinli Guo, Li Yang, Huan Sheng, Dongyang Cui, Da Shao, Ming Chen, Bin Lai, Ping Zheng
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110239- (2024)
Summary: The medial entorhinal cortex (MEC) is crucial for contextual memory, yet its role in context-induced retrieval of morphine withdrawal memory remains unclear. This study investigated the role of the MEC and its projection neurons from MEC lay
Externí odkaz:
https://doaj.org/article/d4656e5811bb4de6baa3b6f45f44cca0