Zobrazeno 1 - 10
of 900
pro vyhledávání: '"systems immunology"'
Autor:
Catherine Byrne, Joshua T. Schiffer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAn unprecedented breadth of longitudinal viral and multi-scale immunological data has been gathered during SARS-CoV-2 infection. However, due to the high complexity, non-linearity, multi-dimensionality, mixed anatomic sampling, and possib
Externí odkaz:
https://doaj.org/article/afe94f068a2c4beeb605509ebef97491
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionPredicting TCR–peptide binding is a complex and significant computational problem in systems immunology. During the past decade, a series of computational methods have been developed for better predicting TCR–peptide binding from amin
Externí odkaz:
https://doaj.org/article/caf92756f0b24a84b2cf94d805e191ce
Autor:
Andrew Fiore-Gartland, Himangi Srivastava, Aaron Seese, Tracey Day, Adam Penn-Nicholson, Angelique Kany Kany Luabeya, Nelita Du Plessis, Andre G. Loxton, Linda-Gail Bekker, Andreas Diacon, Gerhard Walzl, Zachary K. Sagawa, Steven G. Reed, Thomas J. Scriba, Mark Hatherill, Rhea Coler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionDevelopment of an effective vaccine against tuberculosis is a critical step towards reducing the global burden of disease. A therapeutic vaccine might also reduce the high rate of TB recurrence and help address the challenges of drug-resi
Externí odkaz:
https://doaj.org/article/8bd9fb56ab6546c1bd28acda357be680
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Tuberculosis (TB) is caused by infection with the bacterial pathogen Mycobacterium tuberculosis (M.tb) in the respiratory tract. There was an estimated 10.6 million people newly diagnosed with TB, and there were approximately 1.3 million deaths cause
Externí odkaz:
https://doaj.org/article/99ba7d8503ee4c7ebe21c93b308a852c
Autor:
Matteo Barberis, Alejandra Rojas López
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract The interplay between the immune system and the metabolic state of a cell is intricate. In all phases of an immune response, the corresponding metabolic changes shall occur to support its modulation, in addition to the signalling through the
Externí odkaz:
https://doaj.org/article/400f1fedc8f645ff9b9dc4a329780ffe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/a55fdc22db014219846a947642a0cb6c
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 3 (2023)
ABSTRACTA significant surge in research endeavors leverages the vast potential of high-throughput omic technology platforms for broad profiling of biological responses to vaccines and cutting-edge immunotherapies and stem-cell therapies under develop
Externí odkaz:
https://doaj.org/article/8bb18e3410fd4b87834c74af00708fb4
Autor:
Jennifer Connors, Gina Cusimano, Nathan Mege, Kyra Woloszczuk, Emily Konopka, Matthew Bell, David Joyner, Jennifer Marcy, Virginie Tardif, Michele A. Kutzler, Roshell Muir, Elias K. Haddad
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 3 (2023)
In the field of immunology, a systems biology approach is crucial to understanding the immune response to infection and vaccination considering the complex interplay between genetic, epigenetic, and environmental factors. Significant progress has bee
Externí odkaz:
https://doaj.org/article/c0f6d54dbefc41c98846e72a4e1051a7
Autor:
Rainer Knoll, Lorenzo Bonaguro, Jéssica C. dos Santos, Stefanie Warnat-Herresthal, Maartje C. P. Jacobs-Cleophas, Edda Blümel, Nico Reusch, Arik Horne, Miriam Herbert, Melanie Nuesch-Germano, Twan Otten, Wouter A. van der Heijden, Lisa van de Wijer, Alex K. Shalek, Kristian Händler, Matthias Becker, Marc D. Beyer, Mihai G. Netea, Leo A. B. Joosten, Andre J. A. M. van der Ven, Joachim L. Schultze, Anna C. Aschenbrenner
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPeople living with HIV (PLHIV) are characterized by functional reprogramming of innate immune cells even after long-term antiretroviral therapy (ART). In order to assess technical feasibility of omics technologies for application to large
Externí odkaz:
https://doaj.org/article/3678944685db4f8eaf7e3cde8146b3e4