Zobrazeno 1 - 10
of 2 038
pro vyhledávání: '"system biology"'
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/d993537d0c02444caf1c0488d0e9426d
Autor:
Ajay Manaithiya, Ratul Bhowmik, Kunal Bhattacharya, Rajarshi Ray, Sagar Singh Shyamal, Fabrizio Carta, Claudiu T. Supuran, Seppo Parkkila, Ashok Aspatwar
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundMycobacterium tuberculosis (Mtb) carbonic anhydrases (CAs) are critical enzymes that regulate pH by converting CO2 to HCO3−, essential for Mtb’s survival in acidic environments. Inhibiting γ-CAs presents a potential target for novel an
Externí odkaz:
https://doaj.org/article/e1770d03d4f74e38ba37ffcb73779f6e
Autor:
Sonja Kabatnik, Frederik Post, Lylia Drici, Annette Snejbjerg Bartels, Maximilian T. Strauss, Xiang Zheng, Gunvor I. Madsen, Andreas Mund, Florian A. Rosenberger, José Moreira, Matthias Mann
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110620- (2024)
Summary: Colorectal adenomas (CRAs) are potential precursor lesions to adenocarcinomas, currently classified by morphological features. We aimed to establish a molecular feature-based risk allocation framework toward improved patient stratification.
Externí odkaz:
https://doaj.org/article/cd4ca1e2770841e8930a9fcddbe822d3
Autor:
Bahman Panahi, Nahid Hosseinzadeh Gharajeh, Hossein Mohammadzadeh Jalaly, Mohammad Amin Hejazi
Publikováno v:
Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101759- (2024)
Systems biology is an interdisciplinary field that aims to understand complex biological processes at the system level. The data, driven by high-throughput omics technologies, can be used to study the underpinning mechanisms of metabolite production
Externí odkaz:
https://doaj.org/article/1b77a0e173b84beb9c5f7ca2c2a38872
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 4, Pp 585-588 (2024)
The complex pathological mechanism of dry eye involves multiple pathways, such as immunity and inflammation, and requires an integral research program to control the whole picture. Various histological techniques can elucidate the complex physio-path
Externí odkaz:
https://doaj.org/article/7b686d5b1c9246d2ae52831529dcb5b4
Autor:
Florian Rocher, Samir Dou, Géraldine Philippe, Marie-Laure Martin, Philippe Label, Thierry Langin, Ludovic Bonhomme
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Plant diseases are driven by an intricate set of defense mechanisms counterbalanced by the expression of host susceptibility factors promoted through the action of pathogen effectors. In spite of their central role in the establis
Externí odkaz:
https://doaj.org/article/0df9c449e8ca438abaf1a2800127359b
Autor:
Xiaoting Wang, Peiyu Tang, Yitong Gong, Hang Yao, Mingpeng Liang, Hongxia Qu, Xiao Han, Qiusheng Zheng, Zhen Shi, Defang Li, Qingling Jiang
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110382- (2024)
Summary: Bombinin-BO1 (BO1), a bombinin peptide derived from the skin secretion of Bombina orientalis, exhibits broad-spectrum antimicrobial activity. To date, the anticancer effect of BO1 remains unclear. This study confirmed cytotoxicity of BO1 on
Externí odkaz:
https://doaj.org/article/c1a8c46e35be432484540b9730d1a60e
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Ischemic stroke, a significant threat to human life and health, refers to a class of conditions where brain tissue damage is induced following decreased cerebral blood flow. The incidence of ischemic stroke has been steadily increasing globally, and
Externí odkaz:
https://doaj.org/article/f83d1838d64f49088dbfc60a62d46ac1
Autor:
Irene Suilan Zeng
Publikováno v:
Frontiers in Digital Health, Vol 6 (2024)
Externí odkaz:
https://doaj.org/article/998c19b9221b411a8e245636ef592476
Autor:
Ofir Cohn, Gal Yankovitz, Michal Mandelboim, Naama Peshes-Yaloz, Rachel Brandes, Eran Bacharach, Irit Gat-Viks
Publikováno v:
mSystems, Vol 9, Iss 4 (2024)
ABSTRACTSecondary bacterial challenges during influenza virus infection “superinfection”) cause excessive mortality and hospitalization. Here, we present a longitudinal study of bulk gene expression changes in murine lungs during superinfection,
Externí odkaz:
https://doaj.org/article/af57112dbdcd410c931a1e221f45bd12