Zobrazeno 1 - 8
of 8
pro vyhledávání: '"synucleinopathie"'
Autor:
Piero Parchi, Simone Baiardi, Vincenzo Donadio, Sabina Capellari, Corinne Quadalti, Rocco Liguori, Marcello Rossi, Angela Mammana
Publikováno v:
Movement Disorders
Background: Evidence suggests that skin represents a suitable matrix for demonstrating α-synuclein oligomers as a diagnostic biomarker for Lewy body disease. Objective: The objective of this study was to evaluate the diagnostic performance of skin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b10de634087ad936e37b0590ef2a4c
http://europepmc.org/articles/PMC8518528
http://europepmc.org/articles/PMC8518528
Autor:
Maria Francesca Beatino, Ciro De Luca, Nicole Campese, Elisabetta Belli, Rebecca Piccarducci, Linda Giampietri, Claudia Martini, Giulio Perugi, Gabriele Siciliano, Roberto Ceravolo, Andrea Vergallo, Harald Hampel, Filippo Baldacci
α-syn aggregates represent the pathological hallmark of synucleinopathies as well as a frequent copathology (almost 1/3 of cases) in AD. Recent research indicates a potential role of α-syn species, measured in CSF with conventional analytical techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06a9f74cb3fa866fd58897879989bbc
Autor:
Rebekah L.S. Summers, Michele T.M. Hu, Petr Dusek, Mitchell G. Miglis, Jennifer Zitser, Charles H. Adler, Kaylena A. Ehgoetz Martens, Alex Iranzo, Jun Liu, Claudio Liguori, Christine Lo, Annette Janzen, Klaus L. Leenders, Dallah Yoo, Dario Arnaldi, Giuseppe Plazzi, Michal Rolinski, Bradley F. Boeve, Elena Antelmi, Irene Dall'Antonia, Monica Puligheddu, Nico J. Diederich, Luca Baldelli, Wiebke Hermann, Jan Rusz, Raffaele Ferri, Jee Young Lee, Matteo Cesari, Simon J.G. Lewis, Ambra Stefani, Anastasia Kuzkina, Ziv Gan-Or, Federica Provini, Birgit Högl, Kathrin Doppler, Jiri Nepozitek, Jean Gagnon, Wolfgang H. Oertel
Publikováno v:
The lancet / Neurology 20(8), 671-684 (2021). doi:10.1016/S1474-4422(21)00176-9
Patients with isolated rapid-eye-movement sleep behaviour disorder (RBD) are commonly regarded as being in the early stages of a progressive neurodegenerative disease involving alpha-synuclein pathology, such as Parkinson's disease, dementia with Lew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2120c62b366abbae4e6071d09eb071c
https://hdl.handle.net/11380/1251553
https://hdl.handle.net/11380/1251553
Autor:
Annagrazia Cecere, Giorgio Barletta, Pietro Cortelli, Giovanna Calandra-Buonaura, Francesca Baschieri, Pietro Guaraldi
Background According to expert opinion, orthostatic hypotension (OH) associated to a change in heart rate (ΔHR) less than 15 bpm suggests neurogenic OH (NOH). Recently, the ratio between HR and systolic blood pressure changes at 3 min of tilt test (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2875560eb5aa02865d1992dc97e58bdb
http://hdl.handle.net/11585/794202
http://hdl.handle.net/11585/794202
Autor:
Uladzislau Rudakou, Edward A. Fon, Petra Oliva, Guy A. Rouleau, Yves Dauvilliers, Elena Antelmi, Birgit Högl, Anna Heidbreder, Jean-François Trempe, Christopher Liong, Bouchra Ouled Amar Bencheikh, Pavlina Wolf, Isabelle Arnulf, Luigi Ferini-Strambi, A. Desautels, Jennifer A. Ruskey, Peter Young, Nicolas Dupré, Valérie Cochen De Cock, Giuseppe Plazzi, Lior Greenbaum, Michele T.M. Hu, Lynne Krohn, Roy N. Alcalay, Guillaume Lamoureux, Ziv Gan-Or, Xiaokui Kate Zhang, Jacques Montplaisir, S. Hassin-Baer, Dan Spiegelman, Ronald B. Postuma, Ambra Stefani, Jean-François Gagnon, Christelle Charley Monaca, Benoît Vanderperre, Sandra B. Laurent, Tugba N. Ozturk
Publikováno v:
Annals of Neurology
Annals of Neurology, Wiley, 2019, 87 (1), pp.139-153. ⟨10.1002/ana.25629⟩
Annals of Neurology, Wiley, 2019, 87 (1), pp.139-153. ⟨10.1002/ana.25629⟩
Objective The TMEM175/GAK/DGKQ locus is the 3rd strongest risk locus in genome-wide association studies of Parkinson disease (PD). We aimed to identify the specific disease-associated variants in this locus, and their potential implications. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6784f7176e44e8bfcfec1f404e8e988b
https://pubmed.ncbi.nlm.nih.gov/31658403
https://pubmed.ncbi.nlm.nih.gov/31658403
Publikováno v:
Frontiers in Neuroscience
Metal ions are key elements in organisms' life acting like cofactors of many enzymes but they can also be potentially dangerous for the cell participating in redox reactions that lead to the formation of reactive oxygen species (ROS). Any factor indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acda08d00ad62b18ba0c99398936b762
Autor:
Chiara Zurzolo, Saïda Abounit, Ronald Melki, Jean-Christophe Olivo-Marin, Seng Zhu, Luc Bousset, Frida Loria, Fabrice de Chaumont, Laura Pieri
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2016, 35 (19), pp.2120-2138. ⟨10.15252/embj.201593411⟩
The EMBO Journal
EMBO Journal, 2016, 35 (19), pp.2120-2138. ⟨10.15252/embj.201593411⟩
EMBO Journal, EMBO Press, 2016, 35 (19), pp.2120-2138. ⟨10.15252/embj.201593411⟩
The EMBO Journal
EMBO Journal, 2016, 35 (19), pp.2120-2138. ⟨10.15252/embj.201593411⟩
International audience; Synucleinopathies such as Parkinson's disease are characterized by the pathological deposition of misfolded α-synuclein aggregates into inclusions throughout the central and peripheral nervous system. Mounting evidence sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e857aba3d5d76a3d891052e2400f8068
http://hdl.handle.net/11588/816239
http://hdl.handle.net/11588/816239
Autor:
Montagna P., PROVINI, FEDERICA
This chapter describes some sleep disorders and neurovegetative diseases characterized by abnormal protein deposits such as prion protein diseases, synucleinopathies and taupathies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4094::d7704ff534e45b14b33017318f7b7b46
http://hdl.handle.net/11585/101776
http://hdl.handle.net/11585/101776