Synthesis and anticancer activity of new pyrrolocarbazoles and pyrrolo-beta-carbolines

Autor: M. Boisbrun M. Leonce S. Pfeiffer B. Renard P. Lozach O. Meijer L. Lansiaux A. Bailly C. Sapi J., Laronze, J. Y., Laronze, Meijer, L., Lozach, O.

Publikováno v: Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2005, 13, pp.2263-83
Bioorganic and Medicinal Chemistry, 2005, 13, pp.2263-83

Bended' 1, 3 or 'linear' 2 pyrrolidino-fused (aza)carbazoles were prepared and screened towards a few cancer-related targets. Whereas 'bended' derivatives 1 and 3 proved to be weakly toxic, several members of the 'linear' family strongly interact wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a814110e08757a560ec443721b9e7013
https://hal.archives-ouvertes.fr/hal-00018730