Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation

Autor: Céline Loot, Aleksandra Nivina, Guillaume Cambray, Rocío López-Igual, Jose Antonio Escudero, Didier Mazel

Publikováno v: Biotechnology and Bioengineering
Biotechnology and Bioengineering, 2018, 115 (1), pp.184-191. ⟨10.1002/bit.26450⟩
Biotechnology and Bioengineering, Wiley, 2018, 115 (1), pp.184-191. ⟨10.1002/bit.26450⟩

Synthetic DNA design needs to harness the many information layers embedded in a DNA string. We previously developed the Evolutionary Landscape Painter (ELP), an algorithm that exploits the degeneracy of the code to increase protein evolvability. Here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e99e9698b77992f6b570633d0ca4f1b
https://doi.org/10.1002/bit.26450

Recombination-dependent repair of DNA double-strand breaks with purified proteins from Escherichia coli

Autor: Stanislav Dusko Ehrlich, E Cassuto, Dmitry I. Cherny, Patrice Morel

Publikováno v: Journal of Biological Chemistry 27 (272), 17091-17096. (1997)
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1997, 272 (27), pp.17091-17096. ⟨10.1074/jbc.272.27.17091⟩

We have developed an in vitro system in which repair of DNA double-strand breaks is performed by purified proteins of Escherichia coli. A segment was deleted from a circular duplex DNA molecule by restriction at two sites. 3′ single-stranded overha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503314bec8c0f6f4d992af81bcdbd32b
http://prodinra.inra.fr/record/136552

Role of lysophosphatidic acid in vascular smooth muscle cell proliferation.

Autor: Liu Y; Department of Nephrology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China, 130033., Chen F; Department of Dermatology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China, 130033., Ji L; Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China, 130033., Zhang L; Department of Gastroenterology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China, 130033., Xu YJ; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Center, and Department of Physiology and Pathophysiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R2H 2A6, Canada., Dhalla NS; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Center, and Department of Physiology and Pathophysiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R2H 2A6, Canada.

Publikováno v: Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2020 Feb; Vol. 98 (2), pp. 103-110. Date of Electronic Publication: 2019 Aug 01.