Zobrazeno 1 - 10
of 625
pro vyhledávání: '"synovial inflammation"'
Autor:
Yasi Deng, Hao Zheng, Shiqi Liu, Ying Deng, Yuxin Chen, Ling Liang, Mengyun Wang, Qingling Xie, Yupei Yang, Bin Li, Juan Huang, Hanwen Yuan, Huanghe Yu, Wei Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Kadsura heteroclita (Roxb) Craib also named Xuetong in Tujia ethnomedicine in China, has been traditionally employed in rheumatoid arthritis (RA) treatment. Our preceding investigations have elucidated that Xuetongsu (XTS), a triterpenoid co
Externí odkaz:
https://doaj.org/article/e968feea6d774dcb9f5fa2c283c44f24
Autor:
Wanvisa Udomsinprasert, Natcha Mookkhan, Thanyalak Tabtimnark, Teerapong Aramruang, Tachatra Ungsudechachai, Wacharapol Saengsiwaritt, Jiraphun Jittikoon, Usa Chaikledkaew, Sittisak Honsawek
Publikováno v:
Bone & Joint Research, Vol 13, Iss 6, Pp 261-271 (2024)
Aims: This study aimed to determine the expression and clinical significance of a cartilage protein, cartilage oligomeric matrix protein (COMP), in knee osteoarthritis (OA) patients. Methods: A total of 270 knee OA patients and 93 healthy controls we
Externí odkaz:
https://doaj.org/article/a922f542859e462fa87e5b9f7f9a7e39
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Recent evidence highlights the role of low-grade synovial inflammation in the progression of osteoarthritis (OA). Inflamed synovium of OA joints detected by imaging modalities are associated with subsequent progression of OA. In this sense,
Externí odkaz:
https://doaj.org/article/b12025d97c9742b480683588472500b1
Autor:
Shi Yi, Tao Huaqiang, Li Xueyan, Zhang Liyuan, Li Chunhui, Sun Wen, Chu Miao, Chen Kai, Zhu Pengfei, Wang Qiang, Gu Chengyong, Wang Liangliang, Yang Xing, Hao Yuefeng
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 82-95 (2023)
Osteoarthritis (OA) is a prevalent and chronic joint disease that affects the aging population, causing pain and disability. Macrophages in synovium are important mediators of synovial inflammatory activity and pathological joint pain. Previous studi
Externí odkaz:
https://doaj.org/article/611fa88370a240b8b72466cf09e91e77
Autor:
Kosuke Norimatsu, Kazuki Nakanishi, Toshiro Ijuin, Shotaro Otsuka, Seiya Takada, Akira Tani, Ryoma Matsuzaki, Teruki Matsuoka, Harutoshi Sakakima
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background Osteoarthritis (OA) is a degenerative joint disease associated with aging, which often leads to joint stiffness and disability. Exercise is one of the most important non-pharmacological treatments and is prescribed as an indispens
Externí odkaz:
https://doaj.org/article/d7550c9adb6c4e73aa27efdf414bee44
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23633- (2024)
Purpose: This study investigates the potential mechanism of moxibustion in the treatment of rheumatoid arthritis (RA) by regulating the neutrophil extracellular trap (NET)/NOD-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasom
Externí odkaz:
https://doaj.org/article/f72234820a764c20bd23db06b9fb55bb
Publikováno v:
Food and Agricultural Immunology, Vol 34, Iss 1 (2023)
ABSTRACTTo evaluate the effect of exosomes secreted by berberine-treated bone marrow-derived mesenchymal stem cells (BMSCs) on synovial inflammation in collagen-induced arthritis (CIA) model. Exosomes were isolated from berberine-treated BMSCs (Ber-B
Externí odkaz:
https://doaj.org/article/e3f1a12fe97d4be0a8c41d5425aa9eb5
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 4, Pp 793-808 (2023)
Abstract Rheumatoid arthritis (RA) is a chronic autoimmune disease of unexplained causes. Its pathological features include synovial tissue hyperplasia, inflammatory cell infiltration in joint cavity fluid, cartilage bone destruction, and joint defor
Externí odkaz:
https://doaj.org/article/f128d3b801b24b88a6ffa92d13c16c81
Autor:
Xue Du, Zongrui Jiang, Guibin Fang, Ruonan Liu, Xingzhao Wen, Yinjuan Wu, Shu Hu, Zhiqi Zhang
Publikováno v:
Bone & Joint Research, Vol 12, Iss 4, Pp 274-284 (2023)
Aims: This study aimed to investigate the role and mechanism of meniscal cell lysate (MCL) in fibroblast-like synoviocytes (FLSs) and osteoarthritis (OA). Methods: Meniscus and synovial tissue were collected from 14 patients with and without OA. MCL
Externí odkaz:
https://doaj.org/article/47a6d00f40d249fa8e9ce12ccbffa589
Autor:
Bella Mehta, Susan Goodman, Edward DiCarlo, Deanna Jannat-Khah, J. Alex B. Gibbons, Miguel Otero, Laura Donlin, Tania Pannellini, William H. Robinson, Peter Sculco, Mark Figgie, Jose Rodriguez, Jessica M. Kirschmann, James Thompson, David Slater, Damon Frezza, Zhenxing Xu, Fei Wang, Dana E. Orange
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background We sought to identify features that distinguish osteoarthritis (OA) and rheumatoid arthritis (RA) hematoxylin and eosin (H&E)-stained synovial tissue samples. Methods We compared fourteen pathologist-scored histology features and
Externí odkaz:
https://doaj.org/article/7177784a35f941ac81d084f7ffcd9e30