Zobrazeno 1 - 10
of 293
pro vyhledávání: '"synaptic specificity"'
Publikováno v:
eLife, Vol 12 (2024)
In the process of synaptic formation, neurons must not only adhere to specific principles when selecting synaptic partners but also possess mechanisms to avoid undesirable connections. Yet, the strategies employed to prevent unwarranted associations
Externí odkaz:
https://doaj.org/article/336a92e6804e4ba999325b179e293725
Publikováno v:
Brain Sciences, Vol 14, Iss 2, p 155 (2024)
Chemical synapses are essential for neuronal information storage and relay. The synaptic signal received or sent from spatially distinct subcellular compartments often generates different outcomes due to the distance or physical property difference.
Externí odkaz:
https://doaj.org/article/4d609b769cba4e62a58df08ef0cd47f1
Autor:
Naveed Aslam
Publikováno v:
Frontiers in Systems Biology, Vol 2 (2023)
How can synaptic efficacies be maintained despite the fast turnover of proteins at synapses? Partially, we know that the synthesis of new proteins is essential for the induction of the late, long-lasting phase of long-term potentiation (L-LTP). Recen
Externí odkaz:
https://doaj.org/article/de0380cb465044d1a9d9ce4341e461db
Autor:
Trevor Moreland, Fabienne E. Poulain
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Precise wiring of neural circuits is essential for brain connectivity and function. During development, axons respond to diverse cues present in the extracellular matrix or at the surface of other cells to navigate to specific targets, where they est
Externí odkaz:
https://doaj.org/article/f3b5d9fc04a44b208b1539b9dfc6d1f8
Autor:
Heike Blockus, Sebi V. Rolotti, Miklos Szoboszlay, Eugénie Peze-Heidsieck, Tiffany Ming, Anna Schroeder, Nuno Apostolo, Kristel M. Vennekens, Phinikoula S. Katsamba, Fabiana Bahna, Seetha Mannepalli, Goran Ahlsen, Barry Honig, Lawrence Shapiro, Joris de Wit, Attila Losonczy, Franck Polleux
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109828- (2021)
Summary: Synaptic connectivity within adult circuits exhibits a remarkable degree of cellular and subcellular specificity. We report that the axon guidance receptor Robo2 plays a role in establishing synaptic specificity in hippocampal CA1. In vivo,
Externí odkaz:
https://doaj.org/article/ca93291c525c4a8aa7c919fed9005f37
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Neural Circuits, Vol 14 (2020)
During development, neurons navigate a tangled thicket of thousands of axons and dendrites to synapse with just a few specific targets. This phenomenon termed wiring specificity, is critical to the assembly of neural circuits and the way neurons mana
Externí odkaz:
https://doaj.org/article/d841b63fde944623ab84b9cf3e6fb999
Autor:
Jiale Fan, Tingting Ji, Kai Wang, Jichang Huang, Mengqing Wang, Laura Manning, Xiaohua Dong, Yanjun Shi, Xumin Zhang, Zhiyong Shao, Daniel A Colón-Ramos
Publikováno v:
eLife, Vol 9 (2020)
Synaptic positions underlie precise circuit connectivity. Synaptic positions can be established during embryogenesis and sustained during growth. The mechanisms that sustain synaptic specificity during allometric growth are largely unknown. We perfor
Externí odkaz:
https://doaj.org/article/2d920636b8eb4f62a6b5ee3b28cc6cfe
Autor:
Nern, Aljoscha, Nguyen, Louis-Vu T., Herman, Tory, Prakash, Saurabh, Clandinin, Thomas R., Zipursky, S. Lawrence, Sanes, Joshua R.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2005 Sep 01. 102(36), 12944-12949.
Externí odkaz:
https://www.jstor.org/stable/3376493