Zobrazeno 1 - 10
of 1 297
pro vyhledávání: '"synaptic proteins"'
Autor:
Matteo Spinelli, Francesco Spallotta, Chiara Cencioni, Francesca Natale, Agnese Re, Alice Dellaria, Antonella Farsetti, Salvatore Fusco, Claudio Grassi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Metabolic disorders such as insulin resistance and type 2 diabetes are associated with brain dysfunction and cognitive deficits, although the underpinning molecular mechanisms remain elusive. Epigenetic factors, such as non-coding RNAs, have
Externí odkaz:
https://doaj.org/article/ba9e5d67e4994df9862d5b340b93ffb4
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-18 (2024)
Abstract Palmitoylation is a type of lipid modification that plays an important role in various aspects of neuronal function. Over the past few decades, several studies have shown that the palmitoylation of synaptic proteins is involved in neurotrans
Externí odkaz:
https://doaj.org/article/25faacc6e9564c959dc4b028dedf76ab
Autor:
Yue‐Ming Zhang, Ru‐Meng Wei, Zong‐Yin Li, Xue‐Yan Li, Kai‐Xuan Zhang, Yi‐Jun Ge, Xiao‐Yi Kong, Xue‐Chun Liu, Gui‐Hai Chen
Publikováno v:
Brain and Behavior, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Introduction Maternal sleep deprivation (MSD), which induces inflammation and synaptic dysfunction in the hippocampus, has been associated with learning and memory impairment in offspring. Melatonin (Mel) has been shown to have anti‐inflam
Externí odkaz:
https://doaj.org/article/62d85babf08f43e89796c9a0e5d3223a
Autor:
Yue‐Ming Zhang, Ya‐Tao Wang, Ru‐Meng Wei, Xue‐Yan Li, Bao‐Ling Luo, Jing‐Ya Zhang, Kai‐Xuan Zhang, Shi‐Kun Fang, Xue‐Chun Liu, Gui‐Hai Chen
Publikováno v:
Brain and Behavior, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Background The inflammation and synaptic dysfunction induced by mitochondrial dysfunction play essential roles in the learning and memory impairment associated with sleep dysfunction. Elamipretide (SS‐31), a novel mitochondrion‐targeted
Externí odkaz:
https://doaj.org/article/a972acd74b8143629cd15b4711aef570
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 5, Pp 1445-1454 (2025)
Cerebral ischemia is a major health risk that requires preventive approaches in addition to drug therapy. Physical exercise enhances neurogenesis and synaptogenesis, and has been widely used for functional rehabilitation after stroke. In this study,
Externí odkaz:
https://doaj.org/article/16598e185ed0401096c7d8a5f34d4d60
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2024)
Oxidative stress, induced by impaired insulin signaling in the brain contributes to cognitive loss in sporadic Alzheimer’s disease (sAD). This study evaluated early hippocampal oxidative stress, pre- and post-synaptic proteins in intraperitoneal (I
Externí odkaz:
https://doaj.org/article/43830fb80df742cd9029b7f1bde5f02e
Autor:
Yue-Ming Zhang, Meng-Ying Zhang, Ru-Meng Wei, Jing-Ya Zhang, Kai-Xuan Zhang, Bao-Ling Luo, Yi-Jun Ge, Xiao-Yi Kong, Xue-Yan Li, Gui-Hai Chen
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
ObjectiveStudies have suggested that prenatal exposure to inflammation increases the risk of neuropsychiatric disorders, including anxiety, depression, and cognitive dysfunction. Because of anatomical and hormonal alterations, pregnant women frequent
Externí odkaz:
https://doaj.org/article/20c967b7881443d192159eddf42c55a1
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/b65faa49f6a742f48a58d374312b394d
Autor:
Siddhita Jadhav, Tos T.J.M. Berendschot, Govindasamy Kumaramanickavel, Eline E.B. De Clerck, Carroll A.B. Webers
Publikováno v:
Endocrine and Metabolic Science, Vol 11, Iss , Pp 100127- (2023)
Diabetic retinopathy (DR) is the most common ophthalmological complication of diabetes mellitus (DM) and a leading cause of preventable visual impairment. In DM, retinal neurodegenerative changes precede microvascular changes which can be assessed by
Externí odkaz:
https://doaj.org/article/ff22ff3b277f4ad08d21d1d76e5a6d0f
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