Zobrazeno 1 - 10
of 905
pro vyhledávání: '"synapse loss"'
Publikováno v:
Animal Cells and Systems, Vol 28, Iss 1, Pp 392-400 (2024)
This study investigates the effect of Licochalcone A (Lico-A), a flavonoid from licorice roots known for its anti-inflammatory, anti-cancer, and antioxidant properties, on NMDA-induced neurotoxicity in primary cultured rat hippocampal neurons. The st
Externí odkaz:
https://doaj.org/article/369395d1a6d64566be30c914ead4c1e2
Publikováno v:
IEEE Access, Vol 12, Pp 156492-156504 (2024)
The key histopathological features of Alzheimer’s disease (AD) include extensive brain shrinkage and amyloid plaques made up of amyloid beta (A $\beta $ ) deposition, as well as neurofibrillary tangles (NFTs) made up of hyperphosphorylated microtub
Externí odkaz:
https://doaj.org/article/5bebaf974d2b4cbbaafa0912241f8869
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Antiretroviral (ARV) drugs have improved prognoses for people living with HIV. However, HIV-associated neurocognitive disorders (HAND) persist despite undetectable viral loads. Some ARVs have been linked to neuropsychiatric effects that
Externí odkaz:
https://doaj.org/article/ef5043e73bc5412282fa621a3208e24d
Autor:
Pan Meng, Xi Zhang, Tong-tong Liu, Jian Liu, Yan Luo, Ming-xia Xie, Hui Yang, Rui Fang, Dong-wei Guo, Zi-yan Zhong, Yu-hong Wang, Jin-Wen Ge
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-19 (2023)
Abstract Background Depression is a neuropsychiatric disease resulting from deteriorations of molecular networks and synaptic injury induced by stress. Traditional Chinese formula Xiaoyaosan (XYS) exert antidepressant effect, which was demonstrated b
Externí odkaz:
https://doaj.org/article/24030f2c58f6484380790d666153ad79
Autor:
Gunel Ayyubova, Nadeem Fazal
Publikováno v:
Brain Sciences, Vol 14, Iss 5, p 434 (2024)
Research indicates that brain-region-specific synapse loss and dysfunction are early hallmarks and stronger neurobiological correlates of cognitive decline in Alzheimer’s disease (AD) than amyloid plaque and neurofibrillary tangle counts or neurona
Externí odkaz:
https://doaj.org/article/f15c2c3b1f6542688ec0f63ae1b58407
Autor:
Sarah M. Carpanini, Megan Torvell, Ryan J. Bevan, Robert A. J. Byrne, Nikoleta Daskoulidou, Takashi Saito, Takaomi C. Saido, Philip R. Taylor, Timothy R. Hughes, Wioleta M. Zelek, B. Paul Morgan
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Complement is involved in developmental synaptic pruning and pathological synapse loss in Alzheimer’s disease. It is posited that C1 binding initiates complement activation on synapses; C3 fragments then tag them for microglial phagocytosi
Externí odkaz:
https://doaj.org/article/c1e6f35fb3074c2aa60306724f5fa309
Autor:
Maheedhar Kodali, Leelavathi N. Madhu, Roxanne L. Reger, Bojana Milutinovic, Raghavendra Upadhya, Sahithi Attaluri, Bing Shuai, Goutham Shankar, Ashok K. Shetty
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
An optimal intranasal (IN) dose of human mesenchymal stem cell-derived extracellular vesicles (hMSC-EVs), 90 min post-traumatic brain injury (TBI), has been reported to prevent the evolution of acute neuroinflammation into chronic neuroinflammation r
Externí odkaz:
https://doaj.org/article/36f3707b4509431c8309c61dea5d49e0
Publikováno v:
Animal Cells and Systems, Vol 0, Iss 0, Pp 1-9 (2021)
Human immunodeficiency virus type I (HIV-1) infection of the CNS produces synapse loss which correlates with cognitive decline in patients with HIV-associated neurocognitive disorders (HAND). Lithium is mood stabilizer of unknown mechanism used to tr
Externí odkaz:
https://doaj.org/article/d034d3d1541b4a76b2e910d2120e686a
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Akademický článek
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