Výsledky vyhledávání - "surrogate neutralization"

Akademický článek

Effect of vaccine dosing intervals on Omicron surrogate neutralization after three doses of BNT162b2

Autor: Martin A. Prusinkiewicz, Sadaf Sediqi, Ying Jie Li, David M. Goldfarb, Michael Asamoah-Boaheng, Nechelle Wall, Pascal M. Lavoie, Brian Grunau

Publikováno v: Heliyon, Vol 9, Iss 6, Pp e17259- (2023)

Background: Increasing the interval between the first and second SARS-CoV-2 vaccine doses enhances vaccine immunogenicity, however the optimal timing of the third vaccine is unknown. In this study, we investigated how the time interval between the fi

Externí odkaz: https://doaj.org/article/5ca3b0649d6243eabff4df88ad1c11a5

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Akademický článek

Validation and Establishment of the SARS-CoV-2 Lentivirus Surrogate Neutralization Assay as a Prescreening Tool for the Plaque Reduction Neutralization Test

Autor: John Merluza, Johnny Ung, Kai Makowski, Alyssia Robinson, Kathy Manguiat, Nicole Mueller, Jonathan Audet, Julie Chih-Yu Chen, James E. Strong, Heidi Wood, Alexander Bello

Publikováno v: Microbiology Spectrum, Vol 11, Iss 1 (2023)

ABSTRACT Neutralization assays are important for understanding and quantifying neutralizing antibody responses toward severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 lentivirus surrogate neutralization assay (SCLSNA) can

Externí odkaz: https://doaj.org/article/8cd110eb4adb4ed6a093025d51035295

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Akademický článek

Persistence of spike-specific immune responses in BNT162b2-vaccinated donors and generation of rapid ex-vivo T cells expansion protocol for adoptive immunotherapy: A pilot study

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionThe BNT162b2 mRNA-based vaccine has shown high efficacy in preventing COVID-19 infection but there are limited data on the types and persistence of the humoral and T cell responses to such a vaccine.MethodsHere, we dissect the vaccine-ind

Externí odkaz: https://doaj.org/article/2de11de2c64c4340a6dfd0c3392288c1

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Akademický článek

Comparison of two assays to detect IgG antibodies to the receptor binding domain of SARS‑CoV‑2 as a surrogate marker for assessing neutralizing antibodies in COVID-19 patients

Autor: Achala Kamaladasa, Banuri Gunasekara, Chandima Jeewandara, Deshni Jayathilaka, Ananda Wijewickrama, Dinuka Guruge, Ruwan Wijayamuni, T.K. Tan, Graham S. Ogg, Alain Townsend, Gathsaurie Neelika Malavige

Publikováno v: International Journal of Infectious Diseases, Vol 109, Iss , Pp 85-89 (2021)

Background: Neutralizing antibodies (NAbs) are important for protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection. In this study, two assays that are correlated with NAbs were compared: the haemagglutination tes

Externí odkaz: https://doaj.org/article/5712b87bf9084995959ff0a66d841af7

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Akademický článek

Detection of SARS-CoV-2 Antibodies: Comparison of Enzyme Immunoassay, Surrogate Neutralization and Virus Neutralization Test

Autor: Tatjana Vilibic-Cavlek, Maja Bogdanic, Ema Borko, Zeljka Hruskar, Denis Zilic, Thomas Ferenc, Irena Tabain, Ljubo Barbic, Mateja Vujica Ferenc, Ivana Ferencak, Vladimir Stevanovic

Publikováno v: Antibodies, Vol 12, Iss 2, p 35 (2023)

Background: Since sensitivity and specificity vary widely between tests, SARS-CoV-2 serology results should be interpreted with caution. Methods: The study included serum samples from patients who had recovered from COVID-19 (n = 71), individuals vac

Externí odkaz: https://doaj.org/article/c284ac4155dc46bf8e7f5ed2a25d29e1

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Akademický článek

Performance of a Surrogate SARS-CoV-2-Neutralizing Antibody Assay in Natural Infection and Vaccination Samples

Autor: Kwok-Hung Chan, Ka-Yi Leung, Ricky-Ruiqi Zhang, Danlei Liu, Yujing Fan, Honglin Chen, Kwok-Yung Yuen, Ivan Fan-Ngai Hung

Publikováno v: Diagnostics, Vol 11, Iss 10, p 1757 (2021)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing antibody (NAb) production is a crucial humoral response that can reduce re-infection or breakthrough infection. The conventional test used to measure NAb production capacity le

Externí odkaz: https://doaj.org/article/101a3f496e4342aea0291d77972cee10

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