Propionibacterium acnes biofilm is present in intervertebral discs of patients undergoing microdiscectomy

Autor: Radim Lipina, Garth A. James, Ondrej Slaby, John C. Baird, Jiri Sana, Nitin N. Bhatia, Christof Birkenmaier, Jeffrey C. Wang, A. Nick Shamie, Assaf Raz, Robert K. Eastlack, Jerry Stonemetz, Filip Ruzicka, Steven R. Garfin, Neel Anand, Elleni Michu, Jonathan E. Schmitz, Philip S. Stewart, Radim Jančálek, Jaspaul S. Gogia, Vincent A. Fischetti, Tana Machackova, Konstantinos Mavrommatis, Michael F. Coscia, Fahad S. Ahmed, Steve T. Fisher, Hana Nosková, Timothy F. Witham, Yu-Po Lee, Manu N. Capoor, Ziya L. Gokaslan, Martin Smrčka, Calvin C. Kuo, Todd Alamin, Sibel Demir-Deviren

Publikováno v: PLoS ONE, Vol 12, Iss 4, p e0174518 (2017)
PLoS ONE
Capoor, Manu N; Ruzicka, Filip; Schmitz, Jonathan E; James, Garth A; Machackova, Tana; Jancalek, Radim; et al.(2017). Propionibacterium acnes biofilm is present in intervertebral discs of patients undergoing microdiscectomy.. PloS one, 12(4), e0174518-e01745e0174518. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/8qn97751

Background In previous studies, Propionibacterium acnes was cultured from intervertebral disc tissue of similar to 25% of patients undergoing microdiscectomy, suggesting a possible link between chronic bacterial infection and disc degeneration. Howev

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http://europepmc.org/articles/PMC5378350?pdf=render