Zobrazeno 1 - 10
of 3 160
pro vyhledávání: '"surface glycoprotein"'
Publikováno v:
Medicine in Omics, Vol 11, Iss , Pp 100036- (2024)
Background: COVID-19 caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome) has created an alarming situation worldwide. The surface (S) glycoprotein of novel coronavirus, encoded by the genome of SARS-CoV-2, plays an role in attachment, fusion as
Externí odkaz:
https://doaj.org/article/566372368014403c8096140af9afeca3
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 2946-2960 (2024)
Targeting the FLT3 receptor and the IL-1R associated kinase 4 as well as the anti-apoptotic proteins MCL1 and BCL2 may be a promising novel approach in the treatment of acute myeloid leukemia (AML). The FLT3 and IRAK4 inhibitor emavusertib (CA4948),
Externí odkaz:
https://doaj.org/article/ab41290b58f549f1851ded0efc64d10f
Autor:
Pavel Nesterov, Patrick Eirich, Ekaterina V. Skorb, Sergey Shityakov, Jens Broscheit, Bodo Sander, Nicola G. Jones, Thomas Dandekar, Markus Engstler
Publikováno v:
Open Research Europe, Vol 4 (2024)
Background Trypanosoma brucei is a protozoan parasite that evades the mammalian host’s adaptive immune response by antigenic variation of the highly immunogenic variant surface glycoprotein (VSG). VSGs form a dense surface coat that is constantly r
Externí odkaz:
https://doaj.org/article/ddb29072febf4c06a2bb28a5758cab18
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 9, Pp 7011-7026 (2023)
Targeting the molecular chaperone HSP90 and the anti-apoptotic proteins MCL1 and BCL2 may be a promising novel approach in the treatment of acute myeloid leukemia (AML). The HSP90 inhibitor PU-H71, MCL1 inhibitor S63845, and BCL2 inhibitor venetoclax
Externí odkaz:
https://doaj.org/article/e9fd06a271dc4970ac830749cb3a1183
Autor:
Alexandr Makarov, Jakub Began, Ileana Corvo Mautone, Erika Pinto, Liam Ferguson, Martin Zoltner, Sebastian Zoll, Mark C. Field
Publikováno v:
Microbial Cell, Vol 10, Iss 2, Pp 18-35 (2023)
The surface proteins of parasitic protozoa mediate functions essential to survival within a host, including nutrient accumulation, environmental sensing and immune evasion. Several receptors involved in nutrient uptake and defence from the innate imm
Externí odkaz:
https://doaj.org/article/74409ac2850f48418d2bea46728c3d49
Autor:
A. V. Semenova, G. F. Sivolobova, A. A. Grazhdantseva, S. A. P’yankov, I. S. Shul’gina, O. S. Taranov, O. V. P’yankov, D. V. Antonets, L. I. Karpenko, E. V. Starostina, M. V. Borgoyakova, A. N. Chikaev, E. V. Gavrilova, R. A. Maksyutov, G. V. Kochneva
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 4, Pp 143-149 (2022)
The aim of the study was to create a highly immunogenic vaccine construct based on a recombinant variant of a replication-defective MVA strain of vaccinia virus, expressing virus-like particles that mimic natural infection with Marburg virus. Materia
Externí odkaz:
https://doaj.org/article/fbb54b5d90c74b5d97a2b3af71b8c995
Autor:
Done Stojanov
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 37, Iss 1 (2023)
The aim of this study was to evaluate the impact of the most frequent Asn501 polar uncharged amino acid mutations upon important structural properties of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) Surface Glycoprotein RBD – hACE2
Externí odkaz:
https://doaj.org/article/9c3b8cd0267840cdac28b3a3f262edfe
Akademický článek
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Autor:
Jaime So, Sarah Sudlow, Abeer Sayeed, Tanner Grudda, Stijn Deborggraeve, Dieudonné Mumba Ngoyi, Didier Kashiama Desamber, Bill Wickstead, Veerle Lejon, Monica R. Mugnier
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Trypanosoma brucei gambiense is the primary causative agent of human African trypanosomiasis (HAT), a vector-borne disease endemic to West and Central Africa. The extracellular parasite evades antibody recognition within the host bloodstream
Externí odkaz:
https://doaj.org/article/0554be76d99843de9dd2daf7e05c92a2
Akademický článek
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