From Simple Cyclic 1,3-Ketoamides to Complex Spirolactams by Supported Heterogeneous Organocatalysis with PS-BEMP

Autor: José Carlos Menéndez, Jean Rodriguez, Aouicha Benmaati, Thierry Constantieux, Xavier Bugaut, Salih Hacini, Hadjira Habib Zahmani

Publikováno v: SYNTHESIS
SYNTHESIS, Georg Thieme Verlag, 2016, 48 (19), pp.3217-3231. ⟨10.1055/s-0035-1561485⟩
Synthesis: Journal of Synthetic Organic Chemistry
Synthesis: Journal of Synthetic Organic Chemistry, 2016, 48 (19), pp.3217-3231. ⟨10.1055/s-0035-1561485⟩

International audience; The reaction between cyclic 1,3-ketoamides and Michael acceptors in the presence of a catalytic amount of a polymer-supported organobase PS-BEMP has been developed for a direct access to spirocyclic 1,3-ketolactams through a d

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https://hal.archives-ouvertes.fr/hal-01415069/file/HAL45'.pdf