Výsledky vyhledávání - "supersaturation dissolution"

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Indomethacin co-amorphous drug-drug systems with improved solubility, supersaturation, dissolution rate and physical stability

Autor: A. Levent Demirel, Hanan Fael

Publikováno v: International journal of pharmaceutics. 600

In this study, new co-amorphous drug systems were designed using a pharmacologically relevant combination to improve the solubility and dissolution of indomethacin. Combinations of indomethacin-paracetamol (IND-PAR) as an anti-inflammatory/pain kille

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce9f596de589fe4b644eea9b0a10bc7
https://pubmed.ncbi.nlm.nih.gov/33675920

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The Increased Dissolution and Oral Absorption of Itraconazole by Nanocrystals with an Endogenous Small-Molecule Surfactant as a Stabilizer

Autor: Sheng Chang, Qiang Yang, Jiahuan Liu, Li Yin, Jihong Han, Lanlan Zong, Xiaohui Pu

Publikováno v: Molecules, Vol 29, Iss 8, p 1769 (2024)

The aim of this study was to develop cholic-acid-stabilized itraconazole nanosuspensions (ITZ-Nanos) with the objective of enhancing drug dissolution and oral absorption. A laboratory-scale microprecipitation–high-pressure homogenization method was

Externí odkaz: https://doaj.org/article/9600efcf731a4227aed3c9ef37ffae43

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The Increased Dissolution and Oral Absorption of Itraconazole by Nanocrystals with an Endogenous Small-Molecule Surfactant as a Stabilizer.

Autor: Chang, Sheng¹ (AUTHOR) changsheng-pharm@hotmail.com, Yang, Qiang² (AUTHOR) lanlan198903@126.com, Liu, Jiahuan¹ (AUTHOR), Yin, Li² (AUTHOR), Han, Jihong³ (AUTHOR) j.han@keele.ac.uk, Zong, Lanlan² (AUTHOR), Pu, Xiaohui² (AUTHOR) changsheng-pharm@hotmail.com

Publikováno v: Molecules. Apr2024, Vol. 29 Issue 8, p1769. 13p.

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Investigation of the preparation, characterization, and whitening activity of co-amorphous glabridin and oxymatrine.

Autor: Liang, Peiyi, Hu, Yi, Wang, Zhuxian, Guo, Yinglin, Chen, Hongkai, Jiang, CuiPing, Zeng, Quanfu, Shen, Chunyan, Wu, Yufan, Liu, Li, Yi, Yankui, Zhu, Hongxia, Yang, Zhijun, Liu, Qiang

Publikováno v: CrystEngComm; 12/7/2023, Vol. 25 Issue 45, p6252-6265, 14p

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Supersaturable organic-inorganic hybrid matrix based on well-ordered mesoporous silica to improve the bioavailability of water insoluble drugs.

Autor: Wu, Qiaoli^1,2 (AUTHOR), Feng, Disang¹ (AUTHOR), Huang, Zhengwei¹ (AUTHOR), Chen, Minglong³ (AUTHOR), Yang, Dan¹ (AUTHOR), Pan, Xin³ (AUTHOR), Lu, Chao¹ (AUTHOR), Quan, Guilan¹ (AUTHOR), Wu, Chuanbin^1,3 (AUTHOR)

Publikováno v: Drug Delivery. Dec2020, Vol. 27 Issue 1, p1292-1300. 9p.

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