Zobrazeno 1 - 10 of 71 pro vyhledávání: '"superoxide dismutase 2 (SOD2)"'
1
Akademický článek
Apoptotic vesicles resist oxidative damage in noise-induced hearing loss through activation of FOXO3a-SOD2 pathway
Autor: Xiaotong Huang, Xiaoxing Kou, Ting Zhan, Guokun Wei, Feinan He, Xueli Mao, Haidi Yang
Publikováno v: Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Background Mesenchymal stem cell (MSC) transplantation is a promising therapeutic approach for noise-induced hearing loss (NIHL). As the indispensable role of apoptosis in MSC transplantation was raised, the benefits of MSC-derived apoptotic
Externí odkaz: https://doaj.org/article/f13b255411e54ca79e6b23d47a86f90b
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2
Akademický článek
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3
Akademický článek
Nimbolide Inhibits SOD2 to Control Pancreatic Ductal Adenocarcinoma Growth and Metastasis
Autor: Tugba Mehmetoglu-Gurbuz, Rajkumar Lakshmanaswamy, Karla Perez, Mayra Sandoval, Casandra A. Jimenez, Jackelyn Rocha, Rachel Madeline Goldfarb, Courtney Perry, Alejandra Bencomo, Nishkala Neela, Jose A. Barragan, Raquel Sanchez, Risa Mia Swain, Ramadevi Subramani
Publikováno v: Antioxidants, Vol 12, Iss 10, p 1791 (2023)
Reactive oxygen species are frequently associated with various cancers including pancreatic ductal adenocarcinomas (PDACs). Superoxide dismutase 2 (SOD2) is an enzyme that plays an important role in reactive oxygen species (ROS) signaling. Investigat
Externí odkaz: https://doaj.org/article/78a07b7e2e134efdbf55965e32c7a49e
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4
Akademický článek
Associations between prenatal exposure to cadmium and lead with neural tube defect risks are modified by single-nucleotide polymorphisms of fetal MTHFR and SOD2: a case–control study
Autor: Mengyuan Liu, Jinhui Yu, Zaiming Su, Ying Sun, Yaqiong Liu, Qing Xie, Zhiwen Li, Linlin Wang, Jie Zhang, Lei Jin, Aiguo Ren
Publikováno v: Environmental Health, Vol 20, Iss 1, Pp 1-10 (2021)
Abstract Background Prenatal exposure to heavy metals is implicated in the etiology of birth defects. We investigated whether concentrations of cadmium (Cd) and lead (Pb) in umbilical cord tissue are associated with risk for neural tube defects (NTDs
Externí odkaz: https://doaj.org/article/e3f8009da4bc4019bde03eccb85f1632
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5
Akademický článek
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6
Akademický článek
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7
Akademický článek
Effect of Borrelia burgdorferi Outer Membrane Vesicles on Host Oxidative Stress Response
Autor: Keith Wawrzeniak, Gauri Gaur, Eva Sapi, Alireza G. Senejani
Publikováno v: Antibiotics, Vol 9, Iss 5, p 275 (2020)
Outer membrane vesicles (OMVs) are spherical bodies containing proteins and nucleic acids that are released by Gram-negative bacteria, including Borrelia burgdorferi, the causative agent of Lyme disease. The functional relationship between B. burgdor
Externí odkaz: https://doaj.org/article/caf5b6bd82fc4984865a215ca27bde13
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8
Bicalutamide Exhibits Potential to Damage Kidney via Destroying Complex I and Affecting Mitochondrial Dynamics
Autor: Kuan-Chou Chen, Chang-Rong Chen, Chang-Yu Chen, Chiung-Chi Peng, Robert Y. Peng
Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 1; Pages: 135
Journal of Clinical Medicine, Vol 11, Iss 135, p 135 (2022)
Journal of Clinical Medicine
Bicalutamide (Bic) is an androgen deprivation therapy (ADT) for treating prostate cancer, while ADT is potentially associated with acute kidney injury. Previously, we recognized Bic induced renal mitochondria dysfunction in vitro and in vivo via the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936216cd425cdf97a448b0a387bce37a
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9
A risk stratification model based on four novel biomarkers predicts prognosis for patients with renal cell carcinoma
Autor: Susumu Kageyama, Takahiro Isono, Tetsuya Yoshida, Takeshi Yuasa, Junji Yonese, Tokuhiro Chano, Akihiro Kawauchi, Shigehisa Kubota, Ryoji Kushima
Publikováno v: World Journal of Surgical Oncology, Vol 18, Iss 1, Pp 1-11 (2020)
World Journal of Surgical Oncology
Background:Accurate prediction of the prognosis of RCC using a single biomarker is challenging due to the genetic heterogeneity of the disease. However, it is essential to develop an accurate system to allow better patient selection for optimal treat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03f4ccaca610f977922f7b0e305ee7d
https://doi.org/10.1186/s12957-020-02046-9
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10
BRAF Mutant Melanoma Adjusts to BRAF/MEK Inhibitors via Dependence on Increased Antioxidant SOD2 and Increased Reactive Oxygen Species Levels
Autor: Hima Patel, Long Yuan, Rosalin Mishra, Xin Wei, Joan T. Garrett, Samar Alanazi, Zhijun Ma
Publikováno v: Cancers
Volume 12
Issue 6
Cancers, Vol 12, Iss 1661, p 1661 (2020)
B-Rapidly Accelerated Fibrosarcoma (BRAF) mutations are found in about 50% of melanoma patients. Treatment with Food and Drug Administration (FDA)-approved BRAF and MAP/ERK kinase (MEK) inhibitors has improved progression free and overall survival of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43541ecd96f5f8d35f3016bd14b26582
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