Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium

Autor: Ana Álvarez-Barrios, Lydia Álvarez, Enol Artime, Montserrat García, Imre Lengyel, Rosario Pereiro, Héctor González-Iglesias

Publikováno v: Frontiers in Nutrition, Vol 10 (2023)

The retinal pigment epithelium (RPE) is progressively degenerated during age-related macular degeneration (AMD), one of the leading causes of irreversible blindness, which clinical hallmark is the buildup of sub-RPE extracellular material. Clinical o

Externí odkaz: https://doaj.org/article/4a01447d7175445c85bdc5e121044bfc

Drusen in patient-derived hiPSC-RPE models of macular dystrophies

Autor: Galloway, Chad A., Dalvi, Sonal, Hung, Sandy S. C., MacDonald, Leslie A., Latchney, Lisa R., Wong, Raymond C. B., Guymer, Robyn H., Mackey, David A., Williams, David S., Chung, Mina M., Gamm, David M., Pébay, Alice, Hewitt, Alex W., Singh, Ruchira

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2017 Sep . 114(39), E8214-E8223.

Externí odkaz: https://www.jstor.org/stable/26488065

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Late‐onset retinal degeneration pathology due to mutations in CTRP5 is mediated through HTRA1

Autor: Anil Kumar Chekuri, Donita Garland, Suresh Subramani, Peter X. Shaw, Chloe M. Stanton, Angel Soto-Hermida, Pooja Biswas, Shyamanga Borooah, David S. Goodsell, Virender B. Kumar, Caroline Hayward, Radha Ayyagari, Katarzyna Zientara-Rytter, Marina voronchikhina

Publikováno v: Aging Cell
Chekuri, A, Zientara-Rytter, K, Soto-Hermida, A, Borooah, S, Voronchikhina, M, Biswas, P, Kumar, V, Goodsell, D, Hayward, C, Shaw, P, Stanton, C, Garland, D, Subramani, S & Ayyagari, R 2019, ' Late-onset retinal degeneration pathology de to mutations in CTRP5 is mediated through HTRA1 ', Aging Cell, vol. 18, no. 6, e13011 . https://doi.org/10.1111/acel.13011

Late‐onset retinal degeneration (L‐ORD) is an autosomal dominant macular degeneration characterized by the formation of sub‐retinal pigment epithelium (RPE) deposits and neuroretinal atrophy. L‐ORD results from mutations in the C1q‐tumor ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd74da514cc0e715cfdb5bdd24b23bbc
https://doi.org/10.1111/acel.13011

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.