Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism

Autor: Marc Delarue, Felix Romain, Jerome Gouge, Sandrine Rosario, Pierre Béguin

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2013, 425 (22), pp.4334-4352. ⟨10.1016/j.jmb.2013.07.009⟩
Journal of Molecular Biology, 2013, 425 (22), pp.4334-4352. ⟨10.1016/j.jmb.2013.07.009⟩

International audience; Terminal deoxynucleotidyltransferase (Tdt) is a non-templated eukaryotic DNA polymerase of the polX family that is responsible for the random addition of nucleotides at the V(D)J junctions of immunoglobulins and T-cell recepto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59028c68803a9c52064bd4a85d088521
https://hal-pasteur.archives-ouvertes.fr/pasteur-02174639

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