Zobrazeno 1 - 10
of 498
pro vyhledávání: '"structural identifiability"'
Publikováno v:
Infectious Disease Modelling, Vol 9, Iss 3, Pp 975-994 (2024)
Parameter identification involves the estimation of undisclosed parameters within a system based on observed data and mathematical models. In this investigation, we employ DAISY to meticulously examine the structural identifiability of parameters of
Externí odkaz:
https://doaj.org/article/4ad77d9e5b9b46e99369ad4380713c95
Publikováno v:
Mathematical Biosciences and Engineering, Vol 21, Iss 4, Pp 5577-5603 (2024)
In this paper we develop a four compartment within-host model of nutrition and HIV. We show that the model has two equilibria: an infection-free equilibrium and infection equilibrium. The infection free equilibrium is locally asymptotically stable wh
Externí odkaz:
https://doaj.org/article/acb94dac47b847f49afa63de3b23d7d1
Akademický článek
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Publikováno v:
Mathematical Biosciences and Engineering, Vol 20, Iss 11, Pp 19527-19552 (2023)
Human immunodeficiency virus (HIV) infection is a major public health concern with 1.2 million people living with HIV in the United States. The role of nutrition in general, and albumin/globulin in particular in HIV progression has long been recogniz
Externí odkaz:
https://doaj.org/article/6eb181eb56004983856c3aa890981e87
Publikováno v:
Mathematics, Vol 12, Iss 18, p 2837 (2024)
This study examines the interactions between healthy target cells, infected target cells, virus particles, and immune cells within an HIV model. The model exhibits two equilibrium points: an infection-free equilibrium and an infection equilibrium. St
Externí odkaz:
https://doaj.org/article/552fb4be48644f4bb825dce9e0bf155a
On the Origins and Rarity of Locally but Not Globally Identifiable Parameters in Biological Modeling
Publikováno v:
IEEE Access, Vol 11, Pp 65457-65467 (2023)
Structural identifiability determines the possibility of estimating the parameters of a model by observing its output in an ideal experiment. If a parameter is structurally locally identifiable, but not globally (SLING), its true value cannot be uniq
Externí odkaz:
https://doaj.org/article/850938da890340cdaee41cde184e9ca4
Publikováno v:
Journal of Biological Dynamics, Vol 16, Iss 1, Pp 412-438 (2022)
We fit an SARS-CoV-2 model to US data of COVID-19 cases and deaths. We conclude that the model is not structurally identifiable. We make the model identifiable by prefixing some of the parameters from external information. Practical identifiability o
Externí odkaz:
https://doaj.org/article/3f6701af34d44a30bee2b5d9a8c2a985
Akademický článek
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Publikováno v:
Epidemics, Vol 41, Iss , Pp 100643- (2022)
If model identifiability is not confirmed, inferences from infectious disease transmission models may not be reliable, so they might result in misleading recommendations. Structural identifiability analysis characterises whether it is possible to obt
Externí odkaz:
https://doaj.org/article/aba40604ae754afe951d5aabd4ffd22d