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Akademický článek

Receptor tyrosine kinase-like orphan receptor 1 inhibitor strictinin exhibits anti-cancer properties against highly aggressive androgen-independent prostate cancer

Autor: Vignesh Sivaganesh, Bela Peethambaran

Publikováno v: Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 6, Pp 1188-1209 (2023)

Aim: It is important to identify anti-cancer compounds that can inhibit specific molecular targets to eradicate androgen-receptor negative (ARneg), androgen-independent (AI) prostate cancer, which is an aggressive form of prostate cancer with limited

Externí odkaz: https://doaj.org/article/fbb1e4bdcdaa4e45a8acaf7d3d700ed2

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Akademický článek

Pu'er tea rich in strictinin and catechins prevents biofilm formation of two cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus

Autor: Man-Hua Liao, Xiu-Ru Wang, Wei-Li Hsu, Jason T.C. Tzen

Publikováno v: Journal of Dental Sciences, Vol 16, Iss 4, Pp 1331-1334 (2021)

Cariogenic bacteria, such as Streptococcus mutans and Streptococcus sobrinus, are main pathogens responsible for human dental caries. Pu'er tea is empirically observed to prevent tooth decay. Besides caffeine and catechins commonly found in oolong te

Externí odkaz: https://doaj.org/article/9efc8960b4194131b8446bd2a54fa531

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Akademický článek

Strictinin: A Key Ingredient of Tea

Autor: Jason T. C. Tzen

Publikováno v: Molecules, Vol 28, Iss 9, p 3961 (2023)

Strictinin is a relatively tiny ellagitannin, which is found in many plants as a minor constituent. Catechins are known as the major constituents in the young leaves of most tea plants, while strictinin was found as a major constituent in the Pu’er

Externí odkaz: https://doaj.org/article/4ea336b8631d45c1b03e1d743c700cde

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Akademický článek

Alleviation of Hyperuricemia by Strictinin in AML12 Mouse Hepatocytes Treated with Xanthine and in Mice Treated with Potassium Oxonate

Autor: Kuo-Ching Huang, Yu-Ting Chang, Rosita Pranata, Yung-Hsuan Cheng, Yu-Chi Chen, Ping-Chung Kuo, Yi-Hsuan Huang, Jason T. C. Tzen, Rong-Jane Chen

Publikováno v: Biology, Vol 12, Iss 2, p 329 (2023)

Hyperuricemia, an abnormally high level of blood uric acid, is a major risk factor for gout. Although xanthine oxidase inhibitors were clinically used to lower blood uric acid level, the concerned side effects restricted their utilization. In this st

Externí odkaz: https://doaj.org/article/0543026ddba84210ac46bcddfd81a3a8

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Akademický článek

Strictinin, a Major Ingredient in Yunnan Kucha Tea Possessing Inhibitory Activity on the Infection of Mouse Hepatitis Virus to Mouse L Cells

Autor: Erh-Chuang Tu, Wei-Li Hsu, Jason T. C. Tzen

Publikováno v: Molecules, Vol 28, Iss 3, p 1080 (2023)

Theacrine and strictinin of Yunnan Kucha tea prepared from a mutant variety of wild Pu’er tea plants were two major ingredients responsible for the anti-influenza activity. As the COVID-19 outbreak is still lurking, developing safe and cost-effecti

Externí odkaz: https://doaj.org/article/4aa730af07b54c2b972c12d4acc4cae3

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Akademický článek

Pancreatic lipase inhibition of strictinin isolated from Pu’er tea (Cammelia sinensis) and its anti-obesity effects in C57BL6 mice

Autor: Tzu-Yin Chen, Miki M.C. Wang, Sheng-Kuo Hsieh, Meng-Huang Hsieh, Wen-Ying Chen, Jason T.C. Tzen

Publikováno v: Journal of Functional Foods, Vol 48, Iss , Pp 1-8 (2018)

Strictinin isolated from Pu’er tea was demonstrated to inhibit pancreatic lipase in vitro. In an olive oil tolerance test, the administration of strictinin (100 mg/kg) significantly reduced the blood triglyceride level and increased the fecal oil c

Externí odkaz: https://doaj.org/article/33559768ac454870ae3a2ec0215acd72

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Pu'er tea rich in strictinin and catechins prevents biofilm formation of two cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus

Autor: Wei-Li Hsu, Jason T.C. Tzen, Xiu-Ru Wang, Man-Hua Liao

Publikováno v: Journal of Dental Sciences, Vol 16, Iss 4, Pp 1331-1334 (2021)
Journal of Dental Sciences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b16043712a61375b99c8984c4d6771
http://www.sciencedirect.com/science/article/pii/S1991790221001057

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Assessing Antipsoriatic Effects of Bitter Pu’er Tea and Its Three Major Compounds, Strictinin, Theacrine and Epigallocatechin Gallate, in Imiquimod-Treated Mice

Autor: Pei-Yi Lin, Cian-Fen Jhuo, Nan-Hei Lin, Wen-Ying Chen, Jason T. C. Tzen

Publikováno v: Compounds; Volume 2; Issue 4; Pages: 293-306

Psoriasis is a chronic inflammatory skin disease with hyperproliferation and aberrant differentiation of keratinocytes in association with the elevation of interleukin-17A (IL-17A) and IL-23 levels. In an animal model, psoriasis-like dermatitis was i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e43cb48233960ae89b0eba3cbd352b

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