Zobrazeno 1 - 10
of 10 371
pro vyhledávání: '"stop codon"'
Autor:
Kamila Pawlicka, Tomas Henek, Lukas Uhrik, Lenka Hernychova, Monikaben Padariya, Jakub Faktor, Sławomir Makowiec, Borivoj Vojtesek, David Goodlett, Ted Hupp, Umesh Kalathiya
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Readthrough of a translation termination codon is regulated by ribosomal A site recognition and insertion of near-cognate tRNAs. Small molecules exist that mediate incorporation of amino acids at the stop codon and production of full-length, often fu
Externí odkaz:
https://doaj.org/article/5d9b655acfbe4fd58d4c82057f38f57f
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTChronic alcohol consumption may alter mRNA methylation and expression levels of genes related to addiction and reward in the brain, potentially contributing to alcohol tolerance and dependence. Neuron-like (SH-SY5Y) and non-neuronal (SW620) c
Externí odkaz:
https://doaj.org/article/11bdb85898814fce9515f930437d368e
Publikováno v:
Frontiers in Virology, Vol 4 (2024)
Tombusviridae is a large family of single-stranded, positive-sense RNA plant viruses with uncapped, non-polyadenylated genomes encoding 4–7 open reading frames (ORFs). Previously, we discovered, by high-throughput sequencing of maize and teosinte R
Externí odkaz:
https://doaj.org/article/4f7a5a22f5d441369d275093f3e9a7ca
Autor:
Aiswarya Premchandar, Ruiji Ming, Abed Baiad, Dillon F. Da Fonte, Haijin Xu, Denis Faubert, Guido Veit, Gergely L. Lukacs
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Cystic fibrosis (CF) is a monogenic disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. Premature termination codons (PTCs) represent ∼9% of CF mutations that typically cause severe expression defects of the CFTR
Externí odkaz:
https://doaj.org/article/0054f0d55fa143fcb730664fc66df904
Autor:
Z. J. Kadhim, G. A. Abdulhasan
Publikováno v:
The Iraqi Journal of Agricultural science, Vol 54, Iss 6 (2023)
This study was aimed to investigate the role of some Toll-like receptor 5 (TLR5) and E. coli fliC gene polymorphisms with increased risk to recurrent urinary tract infections (rUTI). From 180 specimens (blood and urine) were collected from women of d
Externí odkaz:
https://doaj.org/article/fd2eddd5128a42118b614b6097c711b7
Autor:
Viggo G. Blomquist, Jacqueline Niu, Papiya Choudhury, Ahmad Al Saneh, Henry M. Colecraft, Christopher A. Ahern
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102032- (2023)
Disease-causing premature termination codons (PTCs) individually disrupt the functional expression of hundreds of genes and represent a pernicious clinical challenge. In the heart, loss-of-function mutations in the hERG potassium channel account for
Externí odkaz:
https://doaj.org/article/d14f2efcb2674b468afef721b506ec77
Akademický článek
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Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/2d203ff709964ba480da3f5d992eb5cc
Autor:
Sarah Takallou, Maryam Hajikarimlou, Mustafa Al-gafari, Jiashu Wang, Thomas David Daniel Kazmirchuk, Kamaledin B. Said, Bahram Samanfar, Ashkan Golshani
Publikováno v:
Biology, Vol 13, Iss 3, p 138 (2024)
Maintaining translation fidelity is a critical step within the process of gene expression. It requires the involvement of numerous regulatory elements to ensure the synthesis of functional proteins. The efficient termination of protein synthesis can
Externí odkaz:
https://doaj.org/article/bf80d5ab9dfd4381aba179e71c29a083