Zobrazeno 1 - 10
of 160
pro vyhledávání: '"stemness maintenance"'
Autor:
Yiqing Zhu, Bang Xiao, Meng Liu, Meiting Chen, Ningqi Xia, Haiyan Guo, Jinfeng Huang, Zhiyong Liu, Fang Wang
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-20 (2023)
Abstract Background The unique expression pattern endows oncofetal genes with great value in cancer diagnosis and treatment. However, only a few oncofetal genes are available for clinical use and the underlying mechanisms that drives the fetal-like r
Externí odkaz:
https://doaj.org/article/c7eb10f6ece14d7491bb4b47208a5657
Autor:
Mengru Ni, Jingqing He, Tao Li, Gan Zhao, Zhengyu Ji, Fada Ren, Jianxin Leng, Mengyan Wu, Ruihua Huang, Pinghua Li, Liming Hou
Publikováno v:
Cells, Vol 13, Iss 8, p 703 (2024)
Muscle satellite cells (MuSCs) are crucial for muscle development and regeneration. The primary pig MuSCs (pMuSCs) is an ideal in vitro cell model for studying the pig’s muscle development and differentiation. However, the long-term in vitro cultur
Externí odkaz:
https://doaj.org/article/8264d81241c34dcc9b917468f52d3ba2
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
C2H2 zinc finger (C2H2-ZF) proteins are the majority group of human transcription factors and they have many different molecular functions through different combinations of zinc finger domains. Hepatocellular carcinoma (HCC) is one of the most preval
Externí odkaz:
https://doaj.org/article/a354e1f785fd49e895aca8e6d1ab257d
Autor:
Baiyang Liu, Yulin Shi, Bo Qin, Dating Cheng, Zhi Nie, Haoqing Zhai, Yao Li, Zhixian Jin, Jun Pu, Dongming Yan, Yongbin Chen, Cuiping Yang
Publikováno v:
MedComm – Oncology, Vol 2, Iss 2, Pp n/a-n/a (2023)
Abstract Gliomas, the most lethal brain tumors, often exhibit resistance to conventional chemotherapy and/or radiotherapy. This study reveals that sertindole, a potent dopamine D2 receptor antagonist primarily designed as an antipsychotic medication
Externí odkaz:
https://doaj.org/article/9bafc589b702454c9c1614efc290a284
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-13 (2021)
Abstract Objective This study was to explore the effect of exosomal miR-155 derived from bone marrow mesenchymal stem cells (BMSCs) on stemness maintenance and drug resistance in MPC-11 multiple myeloma cells. Methods MPC-11 cells were transfected wi
Externí odkaz:
https://doaj.org/article/6064b9b865c0449e869c2128ef23bd19
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The neuronal PAS domain 3 (NPAS3) is a member of the basic helix-loop-helix (bHLH) PAS family of transcription factors and is implicated in psychiatric and neurodevelopmental disorders. NPAS3 is robustly expressed in the cortical ventricle zone (VZ),
Externí odkaz:
https://doaj.org/article/f67da107c0ca4b5a867c11a6a70bcba1
Autor:
Changchun Shao, Xue Yang, Yingying Jing, Xiaojuan Hou, Yihua Huang, Chen Zong, Lu Gao, Wenting Liu, Jinghua Jiang, Fei Ye, Junxia Shi, Qiudong Zhao, Rong Li, Xiaoren Zhang, Lixin Wei
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Background The liver possesses a powerful regeneration ability, which is correlated with the stemness of hepatocytes in the portal vein (PV). However, the mechanism underlying the maintenance of hepatocyte stemness has not been elucidated. H
Externí odkaz:
https://doaj.org/article/59765ebe93bd404082de633dbe08f6ff
Autor:
Lingling Chen, Morgan Carlton, Xiaodan Chen, Navdeep Kaur, Hollie Ryan, Tony J Parker, Zhengmei Lin, Yin Xiao, Yinghong Zhou
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Growing evidence suggests that the pluripotent state of mesenchymal stem cells (MSCs) relies on specific local microenvironmental cues such as adhesion molecules and growth factors. Fibronectin (FN), fibroblast growth factor 2 (FG
Externí odkaz:
https://doaj.org/article/c8cea476d2dc402d8a550c96f74b8493
Autor:
Tingcai Pan, Jiawang Tao, Yan Chen, Jiaye Zhang, Anteneh Getachew, Yuanqi Zhuang, Ning Wang, Yingying Xu, Shenglin Tan, Ji Fang, Fan Yang, Xianhua Lin, Kai You, Yi Gao, Yin-xiong Li
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Chemically strategies to generate hepatic cells from human pluripotent stem cells (hPSCs) for the potential clinical application have been improved. However, producing high quality and large quantities of hepatic cells remain chal
Externí odkaz:
https://doaj.org/article/eab6c58f0e3544548efa07f3885e9cf4
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background Endothelial progenitor cells (EPCs) contribute to reendothelialization and neovascularization and protect against vascular injury and ischemia of various organs. We have previously shown downregulation of microRNA (miR)-126 in EPC
Externí odkaz:
https://doaj.org/article/ad731086172c48b2a9f6b6c203fa2cff