Admission neutrophil-to-lymphocyte ratio predicts length of hospitalization and need for ICU admission in adults with Status Epilepticus

Autor: Sasha Olivo, Alex Buoite Stella, Stefania Pavan, Matteo Cegalin, Giovanni Furlanis, Marta Cheli, Marinella Tomaselli, David Stokelj, Paolo Manganotti

Background and objectives: Status epilepticus (SE) is a time-dependent neurological emergency. The current study evaluated the prognostic value of admission neutrophil-to-lymphocyte ratio (NLR) in patients with status epilepticus. Methods: In this re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e756e4bba788365f121cfb03e101653
https://www.sciencedirect.com/science/article/pii/S1059131123000390

Cholesterol 24-hydroxylase is a novel pharmacological target for anti-ictogenic and disease modification effects in epilepsy

Autor: Alessia Salamone, Gaetano Terrone, Rossella Di Sapia, Silvia Balosso, Teresa Ravizza, Luca Beltrame, Ilaria Craparotta, Laura Mannarino, Sara Raimondi Cominesi, Massimo Rizzi, Alberto Pauletti, Sergio Marchini, Luca Porcu, Till S. Zimmer, Eleonora Aronica, Matthew During, Brett Abrahams, Shinichi Kondo, Toshiya Nishi, Annamaria Vezzani

Publikováno v: Salamone, A, Terrone, G, di Sapia, R, Balosso, S, Ravizza, T, Beltrame, L, Craparotta, I, Mannarino, L, Cominesi, S R, Rizzi, M, Pauletti, A, Marchini, S, Porcu, L, Zimmer, T S, Aronica, E, During, M, Abrahams, B, Kondo, S, Nishi, T & Vezzani, A 2022, ' Cholesterol 24-hydroxylase is a novel pharmacological target for anti-ictogenic and disease modification effects in epilepsy ', Neurobiology of Disease, vol. 173, 105835 . https://doi.org/10.1016/j.nbd.2022.105835
Neurobiology of Disease, 173:105835. Academic Press Inc.
Neurobiology of disease, 173:105835. Academic Press Inc.

Therapies for epilepsy mainly provide symptomatic control of seizures since most of the available drugs do not target disease mechanisms. Moreover, about one-third of patients fail to achieve seizure control. To address the clinical need for disease-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae12c776d0ec093587266e73c4c200c
http://hdl.handle.net/11588/892971

Clinical characterization of status epilepticus in childhood: a retrospective study in 124 patients

Autor: Emilio Franzoni, S. Taormina, Daniela Chiarello, Antonia Parmeggiani, Lucia Maltoni, Chiara Spadoni, Duccio Maria Cordelli, A. Lividini, F. Duranti

Publikováno v: Seizure. 78

Purpose: The aim of this study is to describe demographic data, semiology and etiology in a pediatric population with status epilepticus (SE) and refractory SE (RSE). Method: We retrospectively reviewed patients with the following inclusion criteria:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b161b482c0b1beec6f0cb7aff322f5ff
https://pubmed.ncbi.nlm.nih.gov/32371369

Combining perampanel and ketamine in super refractory post-traumatic status epilepticus: a case report

Autor: Francesco Biaduzzini, Alessandro Dinoto, Stefano Meletti, Marta Cheli, Paolo Manganotti, Erik Roman-Pognuz, Giulia Mazzon, Marinella Tomaselli

Status Epilepticus (SE) is a condition resulting either from the failure of seizure termination mechanisms or from the abnormal activation of prolonged seizure mechanisms. It represents a life-threatening medical emergency associated with high morbid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47c30f5c321ec7c6fb688e424bef1b7
http://hdl.handle.net/11368/3005240

Juvenile absence epilepsy relapsing as recurrent absence status, mimicking transient global amnesia, in an elderly patient

Autor: Lorenzo Muccioli, Laura Licchetta, Carlotta Stipa, Francesca Bisulli, Paolo Tinuper

Publikováno v: Epileptic disorders : international epilepsy journal with videotape. 20(6)

We describe a 68-year-old woman who had typical absence seizures since 14 years of age. The absences were refractory to treatment and persisted into adulthood, with no seizure-free periods until seizure control at 59 years of age. After six years of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73fa80f7644efc74a0e7f0e47c26c092
https://pubmed.ncbi.nlm.nih.gov/30530409