A Proteomic Investigation to Discover Candidate Proteins Involved in Novel Mechanisms of 5-Fluorouracil Resistance in Colorectal Cancer

Autor: Mario Ortega Duran, Sadr ul Shaheed, Christopher W. Sutton, Steven D. Shnyder

Publikováno v: Cells, Vol 13, Iss 4, p 342 (2024)

One of the main obstacles to therapeutic success in colorectal cancer (CRC) is the development of acquired resistance to treatment with drugs such as 5-fluorouracil (5-FU). Whilst some resistance mechanisms are well known, it is clear from the stasis

Externí odkaz: https://doaj.org/article/9076b3eb7a6a4329a3ff599f962ca26c

NADH dehydrogenase complex I is overexpressed in incipient metastatic murine colon cancer cells

Autor: Ariane Schaub Clerigué, Fernando Unda, Irina Kratchmarova, Joana Marquez, Gaskon Ibarretxe, Iker Badiola, Vyacheslav Akimov, Nerea Osinalde

Publikováno v: Oncology Reports
Marquez, J, Kratchmarova, I, Akimov, V, Unda, F, Ibarretxe, G, Clerigué, A S, Osinalde, N & Badiola, I 2019, ' NADH dehydrogenase complex I is overexpressed in incipient metastatic murine colon cancer cells ', Oncology Reports, vol. 41, no. 2, pp. 742-752 . https://doi.org/10.3892/or.2018.6892

Colon cancer is one of the most frequently occurring types of cancers in the world. Primary tumours are treated very efficiently, but the metastatic cases are known to have severe outcomes. Therefore, the aim of the present study was to obtain a grea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d233c964644a63002e29cc90407274f
http://europepmc.org/articles/PMC6313061

Scaffold-free 3D cell culture of primary skin fibroblasts induces profound changes of the matrisome

Autor: Glauco R. Souza, Jörn Dengjel, Bich Vu

Publikováno v: Matrix Biology Plus
Matrix Biology Plus, Vol 11, Iss, Pp 100066-(2021)

The human skin has a highly developed extracellular matrix (ECM) that is vital for proper skin functioning, its 3D architecture playing a pivotal role in support and guidance of resident and invading cells. To establish relevant in vitro models mimic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8987d717333078847571bf504402385b
https://pubmed.ncbi.nlm.nih.gov/34435183

Application of 'omics' sciences to the prediction of bone metastases from breast cancer: State of the art

Autor: Antonella Centonza, Stella D'Oronzo, Franco Silvestris, Domenica Lovero, Raffaele Palmirotta, Marica Gentile, Camillo Porta

Publikováno v: Journal of Bone Oncology, Vol 26, Iss, Pp 100337-(2021)
Journal of Bone Oncology

Highlights • Breast cancer (BC) is the first cause of cancer-related death in women. • Most patients with advanced BC develop bone metastases (BM). • Omics technologies have been applied to identify putative BM “predicting” biomarkers. •

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf002e8f9329f393074877248aa546e
https://doi.org/10.1016/j.jbo.2020.100337

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