Zobrazeno 1 - 10
of 704
pro vyhledávání: '"srebp1"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 10, Pp 11580-11592 (2024)
This study investigated the effects of acupuncture and warm acupuncture on the expression and mechanism of the AMP-activated protein kinase (AMPK) signalling pathway associated with lipid accumulation in the liver tissue of rats with metabolic dysfun
Externí odkaz:
https://doaj.org/article/a9d4873300a14aeeb94511c47f5ad259
Autor:
Yuzhou Xu, Feng Gui, Zhe Zhang, Zhongyang Chen, Tiange Zhang, Yunhan Hu, Huijun Wei, Yuchen Fu, Xinde Chen, Zhihao Wu
Publikováno v:
Thoracic Cancer, Vol 15, Iss 29, Pp 2116-2127 (2024)
Abstract Background Inositol‐requiring enzyme 1 (IRE1) is an endoplasmic reticulum (ER)‐resident transmembrane protein that senses ER stress and mediates an essential arm of the unfolded protein response (UPR). IRE1 reduces ER stress by upregulat
Externí odkaz:
https://doaj.org/article/f859a746fa45469598e66592e078d9f1
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-23 (2024)
Abstract Background Breast cancer (BC) ranks as the third most fatal malignant tumor worldwide, with a strong reliance on fatty acid metabolism. CLDN6, a candidate BC suppressor gene, was previously identified as a regulator of fatty acid biosynthesi
Externí odkaz:
https://doaj.org/article/4efe1a97eb60427aa817c80b7246b5c7
Autor:
Yin‐Hao Shi, Zhi‐De Liu, Ming‐Jian Ma, Guang‐Yin Zhao, Ying‐Qin Zhu, Jie‐Qin Wang, Yang‐Yin‐Hui Yu, Xi‐Tai Huang, Jing‐Yuan Ye, Fu‐Xi Li, Xi‐Yu Wang, Qiong‐Cong Xu, Xiao‐Yu Yin
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract Lipid metabolism reprogramming stands as a fundamental hallmark of cancer cells. Unraveling the core regulators of lipid biosynthesis holds the potential to find promising therapeutic targets in pancreatic ductal adenocarcinoma (PDAC). Here,
Externí odkaz:
https://doaj.org/article/ccd08fa493f848c993f47e5fe1c331bb
Autor:
Ying He, Shasha Qi, Lu Chen, Jinyu Zhu, Linda Liang, Xudong Chen, Hao Zhang, Lvjia Zhuo, Shujuan Zhao, Shuiping Liu, Tian Xie
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 100987- (2024)
Cancer occurrence and development are closely related to increased lipid production and glucose consumption. Lipids are the basic component of the cell membrane and play a significant role in cancer cell processes such as cell-to-cell recognition, si
Externí odkaz:
https://doaj.org/article/1219655c8df046c1ac73ab32e28cc483
Autor:
Yulong Liu, Qisheng Lu, Guoli Han, Yutong Zheng, Jingyue Cao, Longwei Xi, Haokun Liu, Junyan Jin, Zhimin Zhang, Yunxia Yang, Xiaoming Zhu, Dong Han, Shouqi Xie
Publikováno v:
Aquaculture Reports, Vol 36, Iss , Pp 102187- (2024)
A high carbohydrate diet (HCD) induced excessive hepatic de novo lipogenesis, which caused metabolic disorder and impaired the health of fish species. Betulinic acid (BA) has been applied to ameliorate fatty liver and anti-inflammatory in mammals. He
Externí odkaz:
https://doaj.org/article/c60c1db0e51e425ba998f8f03aa9c03c
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 50, Iss 8, Pp 745-752 (2023)
Objective To explore the regulative effect of α-Hederin on the proliferation and invasion of NSCLC and investigate its related molecular mechanism. Methods After A549 and HCC-1833 cells were treated with a concentration gradient of α-Hederin for 24
Externí odkaz:
https://doaj.org/article/33590a9a00c64494a1f78c37ec98876e
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23945- (2024)
Status epilepticus (SE) is a life-threatening disorder that can result in death or severe brain damage, and there is a substantial body of evidence suggesting a strong association between pyroptosis and SE. Sterol regulatory element binding protein 1
Externí odkaz:
https://doaj.org/article/18c68233c49f43bdb082b8c6b0907030
Autor:
Zili Zhou, Shixiu Liang, Zicong Zhou, Jieyi Liu, Jinming Zhang, Xiaojing Meng, Fei Zou, Haijin Zhao, Changhui Yu, Shaoxi Cai
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Lung fibroblast activation is associated with airway remodeling during asthma progression. Stearoyl-CoA desaturase 1 (SCD1) plays an important role in the response of fibroblasts to growth factors. This study aimed to explore the
Externí odkaz:
https://doaj.org/article/7bd166eb80404d20aeaca4f99e793589
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