Zobrazeno 1 - 10
of 2 618
pro vyhledávání: '"src kinase"'
Autor:
Rachel E. Nicoletto, Cayla J. Holdcraft, Ariel C. Yin, Edward P. Retzbach, Stephanie A. Sheehan, Amanda A. Greenspan, Christopher M. Laugier, Jason Trama, Caifeng Zhao, Haiyan Zheng, Gary S. Goldberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Nontransformed cells form heterotypic cadherin junctions with adjacent transformed cells to inhibit tumor cell growth and motility. Transformed cells must override this form of growth control, called “contact normalization”, to invade an
Externí odkaz:
https://doaj.org/article/57de1dc4fa8647f899e49bfc48148f7e
Autor:
Cheng Chen, Yiyi Zhu, Qianping Li, Zhijie Yu, Yicheng Tan, Fanfan Li, Xipeng Chen, Songfu Jiang, Kang Yu, Shenghui Zhang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 286, Iss , Pp 117223- (2024)
Exposure to benzene causes acute myelosuppression and other hematologic disorders. However, the detailed mechanism by which benzene exerts its severe hematotoxicity and potential treatments still require further deciphering and exploration. Herein, w
Externí odkaz:
https://doaj.org/article/f2b19b062d714e5899e7c578c7b97ce2
Publikováno v:
eLife, Vol 13 (2024)
Protein phosphorylation is one of the major molecular mechanisms regulating protein activity and function throughout the cell. Pannexin 1 (PANX1) is a large-pore channel permeable to ATP and other cellular metabolites. Its tyrosine phosphorylation an
Externí odkaz:
https://doaj.org/article/b616afbd76064f0e959ad27fc3921ec4
Autor:
Panagiota Bouti, Bart J. A. M. Klein, Paul J. H. Verkuijlen, Karin Schornagel, Floris P. J. van Alphen, Kees-Karel H. Taris, Maartje van den Biggelaar, Arie J. Hoogendijk, Robin van Bruggen, Taco W. Kuijpers, Hanke L. Matlung
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe importance of CD11b/CD18 expression in neutrophil effector functions is well known. Beyond KINDLIN3 and TALIN1, which are involved in the induction of the high-affinity binding CD11b/CD18 conformation, the signaling pathways that orches
Externí odkaz:
https://doaj.org/article/53bd94c6190c4bc09c41a6251de19372
Publikováno v:
Biosensors, Vol 14, Iss 4, p 206 (2024)
C-terminal Src kinase (CSK) is the major inhibitory kinase for Src family kinases (SFKs) through the phosphorylation of their C-tail tyrosine sites, and it regulates various types of cellular activity in association with SFK function. As a cytoplasmi
Externí odkaz:
https://doaj.org/article/e42473ea8ce34985832b2b5c346805c2
Autor:
Juan Luo, Hailin Zou, Yibo Guo, Tongyu Tong, Liping Ye, Chengming Zhu, Liang Deng, Bo Wang, Yihang Pan, Peng Li
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-17 (2022)
Abstract Breast cancer (BC) has been ranked the most common malignant tumor throughout the world and is also a leading cause of cancer-related deaths among women. SRC family kinases (SFKs) belong to the non-receptor tyrosine kinase (nRTK) family, whi
Externí odkaz:
https://doaj.org/article/6da5a0794afb46b6b7bc96cdc7936608
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology, Vol Volume 15, Pp 2495-2506 (2022)
Todd Schlesinger,1 Eggert Stockfleth,2 Ayman Grada,3 Brian Berman4 1Clinical Research Center of the Carolinas, Charleston, SC, USA; 2Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Bochum, Germany; 3Department of Derma
Externí odkaz:
https://doaj.org/article/e50ce44aef004475a498ac7a01044121
Autor:
Ana Sofia Pinheiro, Vasilios Tsarouhas, Kirsten André Senti, Badrul Arefin, Christos Samakovlis
Publikováno v:
eLife, Vol 12 (2023)
The acquisition of distinct branch sizes and shapes is a central aspect in tubular organ morphogenesis and function. In the Drosophila airway tree, the interplay of apical extracellular matrix (ECM) components with the underlying membrane and cytoske
Externí odkaz:
https://doaj.org/article/0e020977133d4f73a81d7dde7a8c5e7f
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Akademický článek
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