Zobrazeno 1 - 10
of 202
pro vyhledávání: '"spns2"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Endothelial cell (EC) senescence and vascular aging are important hallmarks of chronic metabolic diseases. An improved understanding of the precise regulation of EC senescence may provide novel therapeutic strategies for EC and vascular agin
Externí odkaz:
https://doaj.org/article/509291ee1c5242e989dd285dca3e548e
Autor:
Wei Weng, Hongyu Huang
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36531- (2024)
Objective: Triple-negative breast cancer (TNBC) is a common cancer with high aggressiveness and high mortality in women. Recently, a plenty of studies have indicated that long non-coding RNAs (lncRNAs) exert the crucial function in human cancers, TNB
Externí odkaz:
https://doaj.org/article/225dcc8b190546c4a88be409a36924be
Autor:
Dunnavant, Kyle Jacob
Doctor of Philosophy
In healthy individuals, the autoimmune system is the body's natural defense against foreign materials and organisms. The main tools utilized for this defense mechanism are immune cells. However, in patients suffering from au
In healthy individuals, the autoimmune system is the body's natural defense against foreign materials and organisms. The main tools utilized for this defense mechanism are immune cells. However, in patients suffering from au
Externí odkaz:
https://hdl.handle.net/10919/119439
Publikováno v:
SLAS Discovery, Vol 28, Iss 6, Pp 284-287 (2023)
The sphingosine-1-phosphate (S1P) pathway remains an active area of research for drug discovery because S1P modulators are effective medicine for autoimmune diseases such as multiple sclerosis and ulcerative colitis. As such, other nodes in the pathw
Externí odkaz:
https://doaj.org/article/f30aa10ed599499bad24cce5472fd6c0
Autor:
Shrader, Christopher Wayne
Doctor of Philosophy
Autoimmune diseases are caused when a person's immune system attacks its own healthy cells. In a person with multiple sclerosis, their immune system becomes sensitized to the myelin sheath that covers their neurons in the ce
Autoimmune diseases are caused when a person's immune system attacks its own healthy cells. In a person with multiple sclerosis, their immune system becomes sensitized to the myelin sheath that covers their neurons in the ce
Externí odkaz:
https://hdl.handle.net/10919/118217
Autor:
Burgio, Ariel Louise
Sphingosine 1-phosphate (S1P) is a lipid chemoattractant molecule. Once formed, S1P can be transported extracellularly by S1P transporters spinster homolog 2 (Spns2) or major facilitator domain containing 2B (mfsd2b). In the extracellular space, S1P
Externí odkaz:
http://hdl.handle.net/10919/115126
Akademický článek
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Publikováno v:
Cell Journal, Vol 24, Iss 5, Pp 230-238 (2022)
Objective: Growing evidences have exposed the important roles of long noncoding RNAs (lncRNAs) in the triple negative breast cancer (TNBC) inhibition. The function of glucuronidase beta pseudogene 11 (GUSBP11) in the TNBC occurrence remains obscure.
Externí odkaz:
https://doaj.org/article/725d9479cbeb4479b3b3bfe61ad48b99
Akademický článek
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Akademický článek
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