Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition

Autor: Xionghao Lin, Tatiana Ammosova, Meng S. Choy, Colette A. Pietzsch, Andrey Ivanov, Asrar Ahmad, Yasemin Saygideğer, Namita Kumari, Dmytro Kovalskyy, Aykut Üren, Wolfgang Peti, Alexander Bukreyev, Sergei Nekhai

Publikováno v: Frontiers in Microbiology, Vol 10 (2019)

Ebola virus (EBOV) is a non-segmented negative-sense RNA virus that causes a severe human disease. The ongoing EBOV outbreak in the Eastern part of Democratic Republic of the Congo has resulted to date in over 2500 confirmed cases including over 1500

Externí odkaz: https://doaj.org/article/cef38a91be7c4905b107b9da78868f86

Ebola Virus NP Binding to Host Protein Phosphatase-1 Regulates Capsid Formation.

Autor: Ahmad A; Howard University., Tigabu B; The University of Texas Medical Branch at Galveston., Ivanov A; Howard University., Jerebtsova M; Howard University., Ammosova T; Howard University., Ramanathan P; UTMB: The University of Texas Medical Branch at Galveston., Kumari N; Howard University., Brantner CA; GWU: George Washington University., Pietzsch CA; UTMB: The University of Texas Medical Branch at Galveston., Abdullah G; Howard University., Popratiloff A; GWU: George Washington University., Widen S; UTMB: The University of Texas Medical Branch at Galveston., Bukreyev A; UTMB: The University of Texas Medical Branch at Galveston., Nekhai S; Howard University.

Publikováno v: Research square [Res Sq] 2023 Jun 06. Date of Electronic Publication: 2023 Jun 06.