Cortico-Cerebellar Hyper-Connections and Reduced Purkinje Cells Behind Abnormal Eyeblink Conditioning in a Computational Model of Autism Spectrum Disorder

Autor: Emiliano Trimarco, Pierandrea Mirino, Daniele Caligiore

Publikováno v: Frontiers in Systems Neuroscience, Vol 15 (2021)

Empirical evidence suggests that children with autism spectrum disorder (ASD) show abnormal behavior during delay eyeblink conditioning. They show a higher conditioned response learning rate and earlier peak latency of the conditioned response signal

Externí odkaz: https://doaj.org/article/02f9ffb2990f425499515fb8aa078089

Human Brain Networks: Spiking Neuron Models, Multistability, Synchronization, Thermodynamics, Maximum Entropy Production, and Anesthetic Cascade Mechanisms

Autor: Wassim M. Haddad, Qing Hui, James M. Bailey

Publikováno v: Entropy, Vol 16, Iss 7, Pp 3939-4003 (2014)

Advances in neuroscience have been closely linked to mathematical modeling beginning with the integrate-and-fire model of Lapicque and proceeding through the modeling of the action potential by Hodgkin and Huxley to the current era. The fundamental b

Externí odkaz: https://doaj.org/article/6c25cf8d64bd45cba935f3b51386597b

Virtual deep brain stimulation: Multiscale co-simulation of a spiking basal ganglia model and a whole-brain mean-field model with The Virtual Brain

Autor: Jil M. Meier, Dionysios Perdikis, André Blickensdörfer, Leon Stefanovski, Qin Liu, Oliver Maith, Helge Ü. Dinkelbach, Javier Baladron, Fred H. Hamker, Petra Ritter

Deep brain stimulation (DBS) has been successfully applied in various neurodegenerative diseases as an effective symptomatic treatment. However, its mechanisms of action within the brain network are still poorly understood. Many virtual DBS models an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1cb19bc3947944b9a94fc94aee84a22
https://doi.org/10.17169/refubium-38661

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Formal Neuron Models: Delays Offer a Simplified Dendritic Integration for Free

Autor: Gilles Bernot, Ophélie Guinaudeau, Alexandre Muzy, Daniel Gaffé, Franck Grammont

Publikováno v: Biomedical Engineering Systems and Technologies ISBN: 9783030291952
BIOSTEC (Selected Papers)
Communications in Computer and Information Science book series, extended selected paper from Biomedical Engineering Systems and Technologies conference (BIOSTEC 2018)
SPRINGER. Communications in Computer and Information Science book series, extended selected paper from Biomedical Engineering Systems and Technologies conference (BIOSTEC 2018), pp.167-191, 2019, ⟨10.1007/978-3-030-29196-9_10⟩

International audience; We firstly define an improved version of the spiking neuron model with dendrites introduced in [8] and we focus here on the fundamental mathematical properties of the framework. Our main result is that, under few simplificatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3c23c0ec07eaae5a9d8f149fb0c29b
https://doi.org/10.1007/978-3-030-29196-9_10