Improved sensitivity of an acid sphingomyelinase activity assay using a C6:0 sphingomyelin substrate

Autor: Wei-Lien Chuang, Joshua Pacheco, Samantha Cooper, Jonathan S. Kingsbury, John Hinds, Pavlina Wolf, Petra Oliva, Joan Keutzer, Gerald F. Cox, Kate Zhang

Publikováno v: Molecular Genetics and Metabolism Reports, Vol 3, Iss C, Pp 55-57 (2015)

Short-chain C6-sphingomyelin is an artificial substrate that was used in an acid sphingomyelinase activity assay for a pilot screening study of patients with Niemann–Pick disease types A and B. Using previously published multiplex and single assay

Externí odkaz: https://doaj.org/article/ba46dfa394d047ddbe6badab30e4c1ba

Intracellular Wireless Analysis of Single Cells by Bipolar Electrochemiluminescence Confined in a Nanopipette

Autor: Neso Sojic, Hong-Yuan Chen, Dechen Jiang, Rong Jin, Yuling Wang

Publikováno v: Angewandte Chemie. 132:10502-10506

The inside walls of a nanopipette tip are decorated by a Pt deposit that is used as an open bipolar electrochemiluminescence (ECL) device to achieve intracellular wireless electroanalysis. The synergetic actions of nanopipette and of bipolar ECL lead

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa0179c707693e51ce5df58eb703dd8
https://doi.org/10.1002/ange.202002323

C24:0 and C24:1 sphingolipids in cholesterol-containing, five- and six-component lipid membranes

Autor: Emilio J. González-Ramírez, Jesús Sot, Aritz B. García-Arribas, Alicia Alonso, Félix M. Goñi

Publikováno v: Scientific Reports
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Addi. Archivo Digital para la Docencia y la Investigación
instname
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)

The biophysical properties of sphingolipids containing lignoceric (C24:0) or nervonic (C24:1) fatty acyl residues have been studied in multicomponent lipid bilayers containing cholesterol (Chol), by means of confocal microscopy, differential scanning

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a344ae1cccc8465fccda8542e0046d5
http://hdl.handle.net/10810/49228

Vitamin D receptor expression and acid sphingomyelinase activity in prefrontal region of a learning animal model

Autor: Samuela Cataldi, Michela Codini, Angelo Sidoni, Carmela Conte, Elisabetta Albi, Tommaso Beccari, Giovanna Traina, Corrado Bucherelli, Ivana Ferri, Elisabetta Baldi

Publikováno v: Archives italiennes de biologie. 157(4)

Contextual fear conditioning (CFC) paradigm is routinely used to study fear-based learning in animals and it provides a useful model for understanding fear and anxiety in human. In the present study, such model was used following the previously estab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d7e6ee2cfa1954b80df8ff7ea4fd73
https://pubmed.ncbi.nlm.nih.gov/32323296

Pb(II) Induces Scramblase Activation and Ceramide-Domain Generation in Red Blood Cells

Autor: Emilio J. González-Ramírez, César Martín, Bingen G. Monasterio, Aritz B. García-Arribas, Noemi Jiménez-Rojo, Jesús Sot, Jon V. Busto, F.-Xabier Contreras, Hasna Ahyayauch, Adela Rendón-Ramírez, Félix M. Goñi, Alicia Alonso

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Addi. Archivo Digital para la Docencia y la Investigación
instname
Scientific Reports

The mechanisms of Pb(II) toxicity have been studied in human red blood cells using confocal microscopy, immunolabeling, fluorescence-activated cell sorting and atomic force microscopy. The process follows a sequence of events, starting with calcium e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ee3fc0480e6772216bd6b59e5bbc82
http://hdl.handle.net/10810/29664