Zobrazeno 1 - 10
of 229
pro vyhledávání: '"spectral flow cytometry"'
Autor:
Valerie Coppard, Grisha Szep, Zoya Georgieva, Sarah K. Howlett, Lorna B. Jarvis, Daniel B. Rainbow, Ondrej Suchanek, Edward J. Needham, Hani S. Mousa, David K. Menon, Felix Feyertag, Krishnaa T. Mahbubani, Kourosh Saeb-Parsy, Joanne L. Jones
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
As the dimensionality, throughput and complexity of cytometry data increases, so does the demand for user-friendly, interactive analysis tools that leverage high-performance machine learning frameworks. Here we introduce FlowAtlas: an interactive web
Externí odkaz:
https://doaj.org/article/38abc65bbc2440418eb7722db7fcaa14
Publikováno v:
Cells, Vol 13, Iss 18, p 1552 (2024)
Synthetic biology has advanced in creating artificial microbial and algal communities, but technical and evolutionary complexities still pose significant challenges. Traditional methods, like microscopy and pigment analysis, are limited in throughput
Externí odkaz:
https://doaj.org/article/830a4417ee77435cb3e0745f97b60233
Autor:
Chao Li, Maozhi Xiao, Suxia Geng, Yulian Wang, Lingji Zeng, Peilong Lai, Ying Gong, Xiaomei Chen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionExploring monocytes’ roles within the tumor microenvironment is crucial for crafting targeted cancer treatments.MethodsThis study unveils a novel methodology utilizing four 20-color flow cytometry panels for comprehensive peripheral imm
Externí odkaz:
https://doaj.org/article/619d03afec874c2da889396cae455022
Autor:
Ana Leda F. Longhini, Inés Fernández-Maestre, Margaret C. Kennedy, Matthew G. Wereski, Shoron Mowla, Wenbin Xiao, Scott W. Lowe, Ross L. Levine, Rui Gardner
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIn vivo studies of cancer biology and assessment of therapeutic efficacy are critical to advancing cancer research and ultimately improving patient outcomes. Murine cancer models have proven to be an invaluable tool in pre-clinical studie
Externí odkaz:
https://doaj.org/article/0915b3f94aed4199bef4783713492b06
Autor:
Belinda Camp, Ilka Jorde, Franka Sittel, Alexander Pausder, Andreas Jeron, Dunja Bruder, Jens Schreiber, Sabine Stegemann-Koniszewski
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAllergic asthma has been mainly attributed to T helper type 2 (Th2) and proinflammatory responses but many cellular processes remain elusive. There is increasing evidence for distinct roles for macrophage and dendritic cell (DC) subsets i
Externí odkaz:
https://doaj.org/article/ab7ba096fd1c41d786620dd68e8f5131
Autor:
Pierre Stéphan, Khaled Bouherrou, Yann Guillermin, Anne-Sophie Michallet, Yenkel Grinberg-Bleyer
Publikováno v:
Cells, Vol 13, Iss 17, p 1458 (2024)
Chronic lymphocytic leukemia (CLL) is a B-cell-derived hematologic malignancy whose progression depends on active B-cell receptor (BCR) signaling. Despite the spectacular efficacy of Ibrutinib, an irreversible inhibitor of Bruton tyrosine kinase (BTK
Externí odkaz:
https://doaj.org/article/7efc648b7cfd4e5c95b4a6a99ba0ef13
Autor:
Ivan Odak, Lâle M. Bayir, Lennart Riemann, Ruth Sikora, Jessica Schneider, Yankai Xiao, Nora Möhn, Thomas Skripuletz, Gernot Beutel, Matthias Eder, Arnold Ganser, Reinhold Förster, Christian R. Schultze-Florey, Christian Koenecke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Variability or stability might have an impact on treatment success and toxicity of CD19 CAR T-cells. We conducted a prospective observational study of 12 patients treated with Tisagenlecleucel for CD19+ B-cell malignancies. Using a 31-color spectral
Externí odkaz:
https://doaj.org/article/5786ca34b273415fb85d64d76fb3aa83
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Climate change is increasing ocean temperatures and consequently impacts marine life (e.g., bacterial communities). In this context, studying host–pathogen interactions in marine organisms is becoming increasingly important, not only for ecological
Externí odkaz:
https://doaj.org/article/0f1616df8ec74ca18521e3702eab114c
Autor:
Tom D. Y. Reijnders, Alex R. Schuurman, Jan Verhoeff, Marlous van den Braber, Renée A. Douma, Daniël R. Faber, Alberta G. A. Paul, W. Joost Wiersinga, Anno Saris, Juan J. Garcia Vallejo, Tom van der Poll
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCommunity-acquired pneumonia (CAP) represents a major health burden worldwide. Dysregulation of the immune response plays an important role in adverse outcomes in patients with CAP.MethodsWe analyzed peripheral blood mononuclear cells by 36
Externí odkaz:
https://doaj.org/article/1c395277784f45d4a2292698566e39b7
Autor:
Ravi K. Patel, Rebecca G. Jaszczak, Kwok Im, Nicholas D. Carey, Tristan Courau, Daniel G. Bunis, Bushra Samad, Lia Avanesyan, Nayvin W. Chew, Sarah Stenske, Jillian M. Jespersen, Jean Publicover, Austin W. Edwards, Mohammad Naser, Arjun A. Rao, Leonard Lupin-Jimenez, Matthew F. Krummel, Stewart Cooper, Jody L. Baron, Alexis J. Combes, Gabriela K. Fragiadakis
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In the past decade, high-dimensional single-cell technologies have revolutionized basic and translational immunology research and are now a key element of the toolbox used by scientists to study the immune system. However, analysis of the data genera
Externí odkaz:
https://doaj.org/article/ffd30363f9fe49ad9fc2ddc15a204aa1