Zobrazeno 1 - 10
of 70
pro vyhledávání: '"spatially resolved metabolomics"'
Publikováno v:
Zhipu Xuebao, Vol 45, Iss 6, Pp 739-747 (2024)
Metabolic abnormalities in mammalian joint tissues are closely linked to various diseases, including rheumatoid arthritis and osteoarthritis. The variations of small molecule metabolites within bone joint tissues can affect cell proliferation, drive
Externí odkaz:
https://doaj.org/article/cd2368d479c44eac9f6ce8ca7a49bc58
Autor:
Xinyue Min, Yiran Zhao, Meng Yu, Wenchao Zhang, Xinyi Jiang, Kaijing Guo, Xiangyi Wang, Jianpeng Huang, Tong Li, Lixin Sun, Jiuming He
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 11, Pp n/a-n/a (2024)
Abstract Mass spectrometry imaging (MSI)‐based spatially resolved metabolomics addresses the limitations inherent in traditional liquid chromatography‐tandem mass spectrometry (LC–MS)‐based metabolomics, particularly the loss of spatial conte
Externí odkaz:
https://doaj.org/article/621ca0315ae04fe1abb3d6afe6ec3bbd
Autor:
Haiyan Jiang, Bowen Zheng, Guang Hu, Lian Kuang, Tianyu Zhou, Sizheng Li, Xinyi Chen, Chuangjun Li, Dongming Zhang, Jinlan Zhang, Zengyan Yang, Jiuming He, Hongtao Jin
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 9, Pp 100971- (2024)
Pulmonary fibrosis (PF) is a chronic progressive end-stage lung disease. However, the mechanisms underlying the progression of this disease remain elusive. Presently, clinically employed drugs are scarce for the treatment of PF. Hence, there is an ur
Externí odkaz:
https://doaj.org/article/fa6b8e26a71d487cab3372c9bcbafe37
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 8, Pp 851-861 (2023)
Tumors are spatially heterogeneous tissues that comprise numerous cell types with intricate structures. By interacting with the microenvironment, tumor cells undergo dynamic changes in gene expression and metabolism, resulting in spatiotemporal varia
Externí odkaz:
https://doaj.org/article/35740b452582448480e62c512e53619f
Autor:
Tianrun Xu, Hang Li, Peng Dou, Yuanyuan Luo, Siming Pu, Hua Mu, Zhihao Zhang, Disheng Feng, Xuesen Hu, Ting Wang, Guang Tan, Chuang Chen, Haiyang Li, Xianzhe Shi, Chunxiu Hu, Guowang Xu
Publikováno v:
Advanced Science, Vol 11, Iss 16, Pp n/a-n/a (2024)
Abstract High‐coverage mass spectrometry analysis of single‐cell metabolomics remains challenging due to the extremely low abundance and wide polarity of metabolites and ultra‐small volume in single cells. Herein, a novel concentric hybrid ioni
Externí odkaz:
https://doaj.org/article/cc77e21d86594b7ab3b56ab3199c2bc7
Autor:
Xiangyi Wang, Jin Zhang, Kailu Zheng, Qianqian Du, Guocai Wang, Jianpeng Huang, Yanhe Zhou, Yan Li, Hongtao Jin, Jiuming He
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 7, Pp 776-787 (2023)
Against tumor-dependent metabolic vulnerability is an attractive strategy for tumor-targeted therapy. However, metabolic inhibitors are limited by the drug resistance of cancerous cells due to their metabolic plasticity and heterogeneity. Herein, cho
Externí odkaz:
https://doaj.org/article/aebbdc5b28874308b224fce960eb0fe7
Autor:
Zhuxian Zhu, Jixu Cai, Weiwei Hou, Ke Xu, Xuxiao Wu, Yuanlin Song, Chunxue Bai, Yin-Yuan Mo, Ziqiang Zhang
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTAlthough gut microbiota has been linked to cancer, little is known about the crosstalk between gut- and intratumoral-microbiomes. The goal of this study was to determine whether gut Akkermansia muciniphila (Akk) is involved in the regulation
Externí odkaz:
https://doaj.org/article/f1f96fec4f5d4ad6a0887065e97bedca
Publikováno v:
Metabolites, Vol 14, Iss 4, p 204 (2024)
Casper, a type of transparent mutant-line zebrafish, was generated to overcome the opaque trunk of an adult zebrafish for tumor modeling to realize real-time visualization of transplanted cells in vivo. However, the molecular information at the metab
Externí odkaz:
https://doaj.org/article/156f5a8c31f546b29b77671a19d30740
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Akademický článek
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