Zobrazeno 1 - 10
of 149
pro vyhledávání: '"sp263"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Programmed death-ligand 1 (PD-L1) expression on tumor cells is associated with poor prognosis in several malignancies, while partly contradictory and inconclusive results have been presented for colorectal cancer (CRC). This study
Externí odkaz:
https://doaj.org/article/a055855f16244387bf7a8e28cfcc7d49
Akademický článek
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Autor:
Gurudutt Gupta, Sunil Pasricha, Meenakshi Kamboj, Anila Sharma, N S Nayana, Garima Durga, Anurag Sharma, Sudhir Rawal, Anurag Meh
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 65, Iss 4, Pp 839-843 (2022)
Introduction: High-grade urothelial carcinoma has a different molecular pathway than superficial low grade urothelial carcinoma, and is characterized by genomic instability. The high tumor mutation burden leads to neoantigen formation, evoking an imm
Externí odkaz:
https://doaj.org/article/038fa10399a345a5bdf5a0967e4c867d
Akademický článek
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Autor:
Kyu Sang Lee, Gheeyoung Choe
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 55, Iss 3, Pp 163-170 (2021)
Programmed cell death protein 1/programmed death-ligand 1 (PD-1/PD-L1) inhibition has revolutionized the treatment paradigm of urothelial carcinoma (UC). Several PD-L1 assays are conducted to formulate appropriate treatment decisions for PD-1/PD-L1 t
Externí odkaz:
https://doaj.org/article/f699fd4b52fd486abcd52d9470e6a768
Akademický článek
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Autor:
Magdalena Zajac, Marietta Scott, Marianne Ratcliffe, Paul Scorer, Craig Barker, Hytham Al-Masri, Marlon C. Rebelatto, Jill Walker
Publikováno v:
Diagnostic Pathology, Vol 14, Iss 1, Pp 1-10 (2019)
Abstract Background Antibodies targeting the programmed cell death-1 (PD-1)/PD-ligand 1 (PD-1/PD-L1) checkpoint have shown promising clinical activity in patients with advanced urothelial carcinoma (UC). Expression of PD-L1 in UC tumors has been inve
Externí odkaz:
https://doaj.org/article/4877dc5bab8d486eb643d9fe5d131069
Autor:
Mark Kriegsmann, Stephanie Roessler, Katharina Kriegsmann, Marcus Renner, Rémi Longuespée, Thomas Albrecht, Moritz Loeffler, Stephan Singer, Arianeb Mehrabi, Monika Nadja Vogel, Anita Pathil, Bruno Köhler, Christoph Springfeld, Christian Rupp, Karl Heinz Weiss, Benjamin Goeppert
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Cholangiocarcinoma (CCA) may arise in the intra- or extrahepatic biliary tract and is associated with a poor prognosis. Despite recent advances, to date there is still no established targeted therapeutic approach available. Non-su
Externí odkaz:
https://doaj.org/article/9d64ab94589b438cbe0b99f4c0bf7dcd
Autor:
Pei Yuan, MD, Changyuan Guo, MD, PhD, Lin Li, MD, PhD, Lei Guo, BS, Fanshuang Zhang, PhD, Jianming Ying, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 2, Pp 100102- (2021)
Introduction: Accurate results on the status of programmed cell death-ligand 1 (PD-L1) rely on not only the quality of immunohistochemistry testing but also the accuracy of the pathologic assessments. We explored the intraobserver and interobserver r
Externí odkaz:
https://doaj.org/article/31a403d931da4f30b364d0a318f6c8ed
Autor:
Elena Guerini Rocco, Albino Eccher, Ilaria Girolami, Paolo Graziano, Gabriella Fontanini, Elena Vigliar, Giancarlo Troncone, Massimo Barberis, Patrizia Morbini, Maurizio Martini
Publikováno v:
Diagnostics, Vol 12, Iss 2, p 477 (2022)
The introduction of immunotherapy targeting the programmed death-1 (PD-1)/programmed death-ligand-1 (PD-L1) axis has represented a turning point in the treatment of HNSCC. Harmonization studies comparing the different antibodies and immunohistochemis
Externí odkaz:
https://doaj.org/article/821cefd769aa44de83389996b938ebe3