Zobrazeno 1 - 10
of 476
pro vyhledávání: '"sonic hedgehog (Shh)"'
Publikováno v:
Oral Oncology Reports, Vol 10, Iss , Pp 100494- (2024)
Nevoid basal cell carcinoma syndrome (NBCCS) is a typical autosomal dominant disorder distinguished by malformations in development and an increased susceptibility to cancer. Keratocystic Odontogenic Tumors (KOTs) are highly malignant lesions of the
Externí odkaz:
https://doaj.org/article/b6ddfc94e4af4826b95a97a9218013e6
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Circulating platelets derived from bone marrow megakaryocytes play a central role in thrombosis and hemostasis. Despite being anucleate, platelets express several proteins known to have nuclear niche. These include transcription factors and
Externí odkaz:
https://doaj.org/article/eb8488161e2a4c358d1f5d11100e0272
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background Neural tube defects (NTDs) are one of the most severe congenital abnormalities characterized by failures of the neural tube to close during early embryogenesis. Maternal folate deficiency could impact the occurrence of NTDs, howev
Externí odkaz:
https://doaj.org/article/97596c6dfd2e4cd882a53114ae7ffc24
Autor:
Xiangyu Zhang, Qingbin Liu, Tingting Zhang, Pei Gao, Hui Wang, Lu Yao, Jingwen Huang, Shulong Jiang
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 889-905 (2022)
As there is currently no effective therapy for patients with prostate cancer (PCa) bone metastasis, it was stringent to explore the relevant treatment strategies. Actually, the interaction between cancer cells and bone microenvironment plays importan
Externí odkaz:
https://doaj.org/article/f666a57ab1a74a84875e2822dfe3fa03
Akademický článek
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Akademický článek
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Autor:
Elvan Şahin, Reem Al-towaitee
Publikováno v:
Sakarya Tıp Dergisi, Vol 12, Iss 2, Pp 367-374 (2022)
Palatogenesis is a complicated and precisely balanced process in which malfunctions induce congenital cleft palate, one of the most common embryonic developmental anomaly seen in newborns. Multiple signaling pathways and transcription factors have be
Externí odkaz:
https://doaj.org/article/7a6fd71206b04e2b9d71eba093ad9f82
Autor:
Alfire Sidik, Groves Dixon, Desire M. Buckley, Hannah G. Kirby, Shuge Sun, Johann K. Eberhart
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Background Gene-environment interactions are likely to underlie most human birth defects. The most common known environmental contributor to birth defects is prenatal alcohol exposure. Fetal alcohol spectrum disorders (FASD) describe the ful
Externí odkaz:
https://doaj.org/article/a592c15870db4880a94181c1d34e8337
NKX6-1 mediates cancer stem-like properties and regulates sonic hedgehog signaling in leiomyosarcoma
Autor:
Po-Hsuan Su, Rui-Lan Huang, Hung-Cheng Lai, Lin-Yu Chen, Yu-Chun Weng, Chih-Chien Wang, Chia-Chun Wu
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-15 (2021)
Abstract Background Leiomyosarcoma (LMS), the most common soft tissue sarcoma, exhibits heterogeneous and complex genetic karyotypes with severe chromosomal instability and rearrangement and poor prognosis. Methods Clinical variables associated with
Externí odkaz:
https://doaj.org/article/6ad8d3cb550441c1afe6a070e5904090
Publikováno v:
Animal Cells and Systems, Vol 0, Iss 0, Pp 1-9 (2021)
TRIM46 is a RING finger E3 ligase which belongs to TRIM (tripartite motif-containing) protein family. TRIM46 is required for neuronal polarity and axon specification by driving the formation of parallel microtubule arrays, whereas its embryological f
Externí odkaz:
https://doaj.org/article/50bbb2a39886427caf196301e307694a