Zobrazeno 1 - 10
of 128
pro vyhledávání: '"solute carrier family 7 member 11"'
Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression
Autor:
Yaya Qiao, Meng Su, Huifang Zhao, Huanle Liu, Chenxi Wang, Xintong Dai, Lingling Liu, Guangju Liu, Huanran Sun, Mingming Sun, Jiyan Wang, Zhen Li, Jun Fan, Quan Zhang, Chunshen Li, Fangmin Situ, Jun Xue, Zhenghu Jia, Chunze Zhang, Shuai Zhang, Changliang Shan
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Ferroptosis is a newly identified iron-dependent form of death that is becoming increasingly recognized as a promising avenue for cancer therapy. N6-methyladenosine (m6A) is the most abundant reversible methylation modification in mRNA contr
Externí odkaz:
https://doaj.org/article/e16df1e8d964488fb1e89a09db7e688e
Autor:
Manli Miao, Min Pan, Xu Chen, Jiapan Shen, Ling Zhang, Xiaoxia Feng, Mengting Chen, Guofeng Cui, Huaiyuan Zong, Wen Zhang, Shuang Chang, Fangzhou Xu, Zixi Wang, Dapeng Li, Weiwei Liu, Zhao Ding, Shengquan Zhang, Biao Chen, Xiaojun Zha, Xiaoyun Fan
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103100- (2024)
Th2-high asthma is characterized by elevated levels of type 2 cytokines, such as interleukin 13 (IL-13), and its prevalence has been increasing worldwide. Ferroptosis, a recently discovered type of programmed cell death, is involved in the pathologic
Externí odkaz:
https://doaj.org/article/60518fe64271481faddd3999715f9691
Publikováno v:
环境与职业医学, Vol 40, Iss 12, Pp 1403-1410 (2023)
BackgroundThe accumulation of inorganic arsenic in the liver can lead to liver fibrosis. Solute carrier family 7 member 11 (SLC7A11) and cyclin dependent kinase inhibitor 1A (CDKN1A) are ferroptosis related genes that are abnormally expressed in live
Externí odkaz:
https://doaj.org/article/14c954a38a9c427195c48b76737e3bb1
Autor:
Rafael Rosell, Anisha Jain, Jordi Codony-Servat, Eloisa Jantus-Lewintre, Blake Morrison, Jordi Barretina Ginesta, María González-Cao
Publikováno v:
Cancer Biology & Medicine, Vol 20, Iss 7, Pp 500-518 (2023)
Lung oncogenesis relies on intracellular cysteine to overcome oxidative stress. Several tumor types, including non-small cell lung cancer (NSCLC), upregulate the system xc- cystine/glutamate antiporter (xCT) through overexpression of the cystine tran
Externí odkaz:
https://doaj.org/article/c75dc006ae7f4f98914e3994f585c6bd
Autor:
Xiangying Yan, Yudong Liu, Congchong Li, Xia Mao, Tengteng Xu, Zhixing Hu, Chu Zhang, Na Lin, Ya Lin, Yanqiong Zhang
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Malignant transformation from hepatic fibrosis to carcinogenesis may be a therapeutic target for hepatocellular carcinoma (HCC). The aim of this study was to evaluate anti-cancer efficacy of Pien-Tze-Huang (PZH), and to investigat
Externí odkaz:
https://doaj.org/article/b0d4ab78739146fc887c95eccc275a55
Publikováno v:
MedComm, Vol 4, Iss 6, Pp n/a-n/a (2023)
Abstract Oxaliplatin (OXA) resistance is a major clinic challenge in hepatocellular carcinoma (HCC). Ferroptosis is a kind of iron‐dependent cell death. Triggering ferroptosis is considered to restore sensitivity to chemotherapy. In the present stu
Externí odkaz:
https://doaj.org/article/5abb93a062e143fc9f79c0b3a6d4bfcf
Publikováno v:
International Journal of General Medicine, Vol Volume 16, Pp 481-497 (2023)
Xiangming Fang,1,* Ting Zhang,2,* Zhitao Chen1 1Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College, Hangzhou, People’s Republic of China; 2Department of Pathology, Hangzhou Tongchuang Me
Externí odkaz:
https://doaj.org/article/cb6fec4a16aa4dcd8222553d672be410
Akademický článek
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Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 5, Pp 570-581 (2022)
Solute carrier family 7 member 11 (SLC7A11; also known as xCT), a key component of the cystine/glutamate antiporter, is essential for the maintenance of cellular redox status and the regulation of tumor-associated ferroptosis. Accumulating evidence h
Externí odkaz:
https://doaj.org/article/354e1901ca9442cb90134f2cc0554ff9
Akademický článek
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