Zobrazeno 1 - 10
of 962
pro vyhledávání: '"soluplus®"'
Autor:
Maryam Jahani, Azadeh Asefnejad, Mastafa H. Al-Musawi, Ahmed A. Mohammed, Basma Talib Al-Sudani, Maha Hameed Al-bahrani, Nada A. Kadhim, Mina Shahriari-Khalaji, Hamideh Valizadeh, Fariborz Sharifianjazi, Morteza Mehrjoo, Ketevan Tavamaishvili, Mohamadreza Tavakoli
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Severe cutaneous injuries may not heal spontaneously and may necessitate the use of supplementary therapeutic methods. Electrospun nanofibers possess high porosity and specific surface area, which provide the necessary microenvironment for w
Externí odkaz:
https://doaj.org/article/7deb0637eee646b4bb72406392f0ce79
Publikováno v:
Acta Marisiensis - Seria Medica, Vol 70, Iss 2, Pp 42-49 (2024)
Background and objective: Self-nanomicellizing solid dispersion SNMSD is a new formulation that combines solid dispersion and nanomicelle strategies; the strategy involves utilizing a suitable carrier that self-assembles into nanomicelles when intera
Externí odkaz:
https://doaj.org/article/2e884bd21c484de5b4ef985db41d8807
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39632- (2024)
The efficacy of dasatinib (DAS) in treating hepatocellular carcinoma (HCC) is hindered by its poor bioavailability, limiting its clinical potential. In this study, we explored the use of TPGS-Soluplus micelles as an innovative drug delivery platform
Externí odkaz:
https://doaj.org/article/9a25894dbf8a41d4b02d1680863d2d7b
Autor:
Vinita Patole, Pranita Gaikwad, Shashikant Kharat, Pranali Jadhav, Sanjeevani Deshkar, Prabhanjan Giram
Publikováno v:
Future Pharmacology, Vol 3, Iss 4, Pp 708-730 (2023)
Green tea extract, rich in polyphenols like catechins, has been reported to have pharmacological benefits in patients with hyperlipidemia. The minimal membrane permeability of green tea limits its use in terms of bioavailability. To improve the perme
Externí odkaz:
https://doaj.org/article/3f8a0b50b96744e9823b9ae70de4bd01
Autor:
Iskra Z. Koleva, Christo T. Tzachev
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1156 (2024)
Herein, we present an elegant and simple method for significant improvement of eugenol water solubility using the polymers Soluplus® and Lutrol F 127 as carriers and spray drying as an encapsulation method. The formulations were optimized by adding
Externí odkaz:
https://doaj.org/article/21234654ec8247efbc30bd63c8634080
Publikováno v:
Gels, Vol 10, Iss 8, p 521 (2024)
This study aims to highlight the importance of choosing the appropriate co-polymer or co-polymer mixed combinations in order to design value-added nasal dosage forms. Local therapy of upper respiratory tract-related infections, such as nasal rhinosin
Externí odkaz:
https://doaj.org/article/4280edfa9ea54fc2902bc868b0ac07fb
Publikováno v:
Polymers, Vol 16, Iss 14, p 1961 (2024)
The successful development of an amorphous form of a drug demands the use of process conditions and materials that reduce their thermodynamic instability. For the first time, we have prepared amorphous ibrutinib using the quench-cooling method with v
Externí odkaz:
https://doaj.org/article/2e2a9523aa9a4f27b4a78c32705c25da
Autor:
Yongxiang Zhang, Minglang Ma, Jinyu Yang, Xiaotong Qiu, Lin Xin, Yixing Lu, Huiguo Huang, Zhenling Zeng, Dongping Zeng
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7025 (2024)
The phenylpyrazole derivative 5-amino-3-[1-cyano-2-(3-phenyl-1H-pyrazol-4-yl) vinyl]-1-phenyl-1H-pyrazole-4-carbonitrile (LN002), which was screened out through high-throughput molecular docking for the AOX target, exhibits promising efficacy against
Externí odkaz:
https://doaj.org/article/e4f9a1d18d454a9786dbd8f0d06c6752
Autor:
Hiba Ayad Aziz, Entidhar J. Al-Akkam
Publikováno v:
مجلة كلية الطب, Vol 65, Iss 4 (2024)
Background: Telmisartan is an antihypertensive angiotensin II receptor antagonist drug commonly used to treat hypertension and renal disease. Based on the Biopharmaceutical Classification System. It’s a Class II poorly soluble drug. Objective: To
Externí odkaz:
https://doaj.org/article/ed339862915d47b88dc84823152363d0
Autor:
Ju-Hyeong Woo, Hai V. Ngo, Hy D. Nguyen, Myung-Chul Gil, Chulhun Park, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e23091- (2023)
The aim of this study was to design a novel matrix tablet with enhanced dissolution and pH-independent controlled release of sildenafil citrate (SIL), a drug with pH-dependent solubility, by using solid dispersions (SDs) and polyelectrostatic interac
Externí odkaz:
https://doaj.org/article/6dfbc9ecc056445a8391d43e5a9155b3