Metalloprotease-mediated cleavage of CD95 Ligand

Autor: Vesna Risso, Mélissa Thomas, Blandine Guével, Regis Lavigne, Emmanuelle Com, Sophie Martin, Manon Nivet, Charles Pineau, Luc Negroni, Élodie Lafont, Éric Chevet, Leif A. Eriksson, Matthieu Le Gallo

Publikováno v: FEBS Journal
FEBS Journal, 2023, ⟨10.1111/febs.16737⟩

International audience; CD95 is a member of the TNF receptor superfamily that is ubiquitously expressed in healthy and pathological tissues. Stimulation of CD95 by its physiological ligand CD95L induces its oligomerization leading in turn to the tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e89063653da47427c8766f8c744ca0
https://hal.science/hal-03968369

Innate immunity in the Grid2(Lc/+) mouse model of cerebellar neurodegeneration: glial CD95/CD95L plays a non-apoptotic role in persistent neuron loss-associated inflammatory reactions in the cerebellum

Autor: Jean Mariani, Yannick Bailly, Paul Derer, Béatrice Vernet-der Garabedian

Publikováno v: Journal of Neuroinflammation
Journal of Neuroinflammation, 2013, 10, pp.829. ⟨10.1186/1742-2094-10-65⟩
Journal of Neuroinflammation, BioMed Central, 2013, 10, pp.829. ⟨10.1186/1742-2094-10-65⟩

There is growing evidence that the death receptor CD95 has a wider role in non-apoptotic functions. In the brain, it may contribute to neural death and to the associated inflammatory reaction via a non-apoptotic pathway. Brain injury triggers an infl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0cb0d17ba48cf7b2f6869369e70095f
https://hal.science/hal-01545794