Zobrazeno 1 - 10
of 1 111
pro vyhledávání: '"solid tumour"'
Autor:
Jiamin Gao, Weishan Tan, Luyun Yuan, Haoyue Wang, Junkai Wen, Kexiang Sun, Xin Chen, Shuyun Wang, Wanli Deng
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27220- (2024)
Tumour-associated macrophages (TAMs), particularly M2-TAMs, constitute the largest proportion of immune cells in the solid tumour microenvironment, playing a crucial role in tumour progression and correlating with poor prognosis. TAMs promote the pro
Externí odkaz:
https://doaj.org/article/8ca8b014fd0947ac8656f394661b9013
Autor:
Wei Wang, Yi Zhang, Yachao Zhang, Nai-Kei Wong, Jun Ma, Jie Li, Long Jin, Lidai Wang, Bai-Ou Guan
Publikováno v:
Materials & Design, Vol 234, Iss , Pp 112304- (2023)
With the recent advances in nanomaterials, photothermal therapies (PTT) enabled by deep-tissue penetration with novel nanoagents have offered a new hope for treating cancers. Nevertheless, PTT applications in conventional approaches remain translatio
Externí odkaz:
https://doaj.org/article/12b08f23e6244ccaac247049dad766ed
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/20d813d1121a4fc899e21e772b2862c8
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1918-1927 (2022)
Histone deacetylases (HDACs) are validated targets for the development of anticancer drugs in epigenetics. In the discovery of novel HDAC inhibitors with anticancer potency, the 5-chloro-4-((substituted phenyl)amino)pyrimidine fragment is assembled a
Externí odkaz:
https://doaj.org/article/10b08077a99545c6bd04fa8660e31c54
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 90-106 (2022)
Glioblastoma multiforme persists to be an enigmatic distress in neuro-oncology. Its untethering capacity to thrive in a confined microenvironment, metastasize intracranially, and remain resistant to the systemic treatments, renders this tumour incura
Externí odkaz:
https://doaj.org/article/e65a8c5fab014cc3bc79885a84cc4265
Autor:
John Maher
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 2, Pp n/a-n/a (2023)
Abstract Immunotherapy using chimeric antigen receptor (CAR)‐engineered T‐cells has achieved remarkable impact in the treatment of selected blood cancers. However, meaningful clinical efficacy against nonhaematological malignancies has largely pr
Externí odkaz:
https://doaj.org/article/0973d60252a34340b2dc28d98aad4eba
Akademický článek
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Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 3, Pp 86-95 (2022)
Chimeric antigen receptor (CAR)-T cell therapy is efficacious against many haematological malignancies, but challenges remain when using this cellular immunotherapy for treating solid tumours. Classical 2D in vitro models fail to recapitulate the com
Externí odkaz:
https://doaj.org/article/eaba4ea35d8546e281cfac93783da60e
Autor:
Darko Kučan, Nada Oršolić, Dyana Odeh, Snježana Ramić, Boris Jakopović, Jelena Knežević, Maja Jazvinšćak Jembrek
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11073 (2023)
The aim of this study was to investigate the therapeutic potential of resveratrol in combination with cisplatin on the inhibition of tumour angiogenesis, growth, and macrophage polarization in mice bearing the solid form of an Ehrlich ascites tumour
Externí odkaz:
https://doaj.org/article/2084b7412bf34810953e432f256018d0
Autor:
Clara Vigneron, Julien Charpentier, Sandrine Valade, Jérôme Alexandre, Samy Chelabi, Lola-Jade Palmieri, Nathalie Franck, Valérie Laurence, Jean-Paul Mira, Matthieu Jamme, Frédéric Pène
Publikováno v:
Annals of Intensive Care, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Background Major therapeutic advances including immunotherapy and targeted therapies have been changing the face of oncology and resulted in improved prognosis as well as in new toxic complications. The aim of this study is to appraise the t
Externí odkaz:
https://doaj.org/article/a9a7c1acfb784abb83a1fa8b610b77ac