Zobrazeno 1 - 10
of 301
pro vyhledávání: '"solid lipid nanoparticles (slns)"'
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 15, Iss 1, Pp 1400-1414 (2024)
Central nervous system diseases negatively affect patients and society. Providing successful noninvasive treatments for these diseases is challenging because of the presence of the blood–brain barrier. While protecting the brain’s homeostasis, th
Externí odkaz:
https://doaj.org/article/4f97c1910f18489eac6099561356da45
Akademický článek
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Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 12, Iss 2, Pp 298-308 (2022)
Tyrosine kinase inhibitors (TKIs) are used as targeted therapy for cancer by inhibiting the signaling pathway and tumor growth. Many TKIs got approved by FDA in recent times for the treatment of cancer by oral route. However, the TKIs have formulatio
Externí odkaz:
https://doaj.org/article/55c134963dd146d6ab3ffd988401405c
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 12, Iss 1, Pp 17-33 (2022)
Solid lipid nanoparticles are one of the developed technologies for addressing the bioavailability and targeting issues of drug delivery. In this review article, we attempted to incorporate all the essential details of SLNs like various methods of pr
Externí odkaz:
https://doaj.org/article/d3ca6fd9c04249759ba6ec7d990677c6
Ocular Delivery of Bimatoprost-Loaded Solid Lipid Nanoparticles for Effective Management of Glaucoma
Autor:
Sandeep Divate Satyanarayana, Amr Selim Abu Lila, Afrasim Moin, Ehssan H. Moglad, El-Sayed Khafagy, Hadil Faris Alotaibi, Ahmad J. Obaidullah, Rompicherla Narayana Charyulu
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 1001 (2023)
Glaucoma is a progressive optic neuropathy characterized by a rise in the intraocular pressure (IOP) leading to optic nerve damage. Bimatoprost is a prostaglandin analogue used to reduce the elevated IOP in patients with glaucoma. The currently avail
Externí odkaz:
https://doaj.org/article/563cc78cb5fb42e1ac609de631801ad3
Autor:
Sebastian Scioli-Montoto, Maria Laura Sbaraglini, Jose Sebastian Cisneros, Cecilia Yamil Chain, Valeria Ferretti, Ignacio Esteban León, Vera Alejandra Alvarez, Guillermo Raul Castro, German Abel Islan, Alan Talevi, Maria Esperanza Ruiz
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Pharmacological treatments of central nervous system diseases are always challenging due to the restrictions imposed by the blood–brain barrier: while some drugs can effectively cross it, many others, some antiepileptic drugs among them, display pe
Externí odkaz:
https://doaj.org/article/dfe51642efb141f99c1765b7f99cf51f
Autor:
Shuo Liu, Xinyue Han, Hanyu Liu, Yawen Zhao, Huamei Li, Ilva D. Rupenthal, Zhufen Lv, Yanzhong Chen, Fan Yang, Qineng Ping, Yufang Pan, Dongzhi Hou
Publikováno v:
Drug Delivery, Vol 27, Iss 1, Pp 652-661 (2020)
Montmorillonite-loaded solid lipid nanoparticles with good biocompatibility, using Betaxolol hydrochloride as model drug, were prepared by the melt-emulsion sonication and low temperature-solidification methods and drug bioavailability was significan
Externí odkaz:
https://doaj.org/article/43e45596472e4f7a9bc146174a7b6dc8
Publikováno v:
Frontiers in Nanotechnology, Vol 4 (2022)
Self-assembled nanocarrier drug delivery has received profuse attention in the field of diagnosis and treatment of diseases. These carriers have proved that serious life-threatening diseases can be eliminated evidently by virtue of their characterist
Externí odkaz:
https://doaj.org/article/8a48e40be72d4b62b209e80e2adeee9d
Autor:
Mahmoud H. Teaima, Merhan Taha El-Nadi, Raghda Rabe Hamed, Mohamed A. El-Nabarawi, Rehab Abdelmonem
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 326 (2023)
The study aims to investigate the ability of lyophilized nasal inserts of nanosized atomoxetine HCl solid lipid nanoparticles (ATM-SLNs) to transport atomoxetine (ATM) directly to the brain and overcome the first-pass metabolism. In this case, 16 for
Externí odkaz:
https://doaj.org/article/b43589b50bd042928467d3bedee14548
Publikováno v:
Applied Sciences, Vol 13, Iss 3, p 1726 (2023)
Although solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have been successfully used as drug delivery systems for about 30 years, the usage of these nanoparticles as food-grade nanovehicles for nutraceuticals or bioactive co
Externí odkaz:
https://doaj.org/article/ce6ba6c0785c40349a5b8f412f14acd1