Zobrazeno 1 - 10
of 19
pro vyhledávání: '"small-organic modulators"'
Autor:
Chahrazade El Amri, Dirk Stratmann, Dalila Darmoul, Elodie Bosc, Michèle Reboud-Ravaux, Viktor Magdolen, Sabrina Aït Amiri, Feryel Soualmia
Publikováno v:
Biological Chemistry
Biological Chemistry, 2018, 399, pp.1073-1078. ⟨10.1515/hsz-2017-0336⟩
Biological Chemistry, 2018, 399, pp.1073-1078. ⟨10.1515/hsz-2017-0336⟩
The activity of kallikrein-related peptidase 6 (KLK6) is deregulated in various diseases such as cancer and neurodegenerative diseases. KLK6 is thus considered as an attractive therapeutical target. In this short report, we depict some novel findings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e5851e557b0d9d2d3c00ce62428959
https://hal.science/hal-03966511
https://hal.science/hal-03966511
Autor:
Wu, Chuan‐Shuo1,2 (AUTHOR), Sun, Xin1,2 (AUTHOR), Liu, Li1,2 (AUTHOR), Cheng, Liang1,2,3 (AUTHOR) chengl@iccas.ac.cn
Publikováno v:
Advanced Science. 11/6/2024, Vol. 11 Issue 41, p1-8. 8p.
Akademický článek
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Autor:
Xuan, Guanhua1,2 (AUTHOR), Xun, Luying1,3 (AUTHOR) luying_xun@vetmed.wsu.edu, Xia, Yongzhen1 (AUTHOR) Xiayongzhen2002@sdu.edu.cn
Publikováno v:
mLife. Jun2024, Vol. 3 Issue 2, p231-239. 9p.
Autor:
Berg, Thorsten
Publikováno v:
Angewandte Chemie. International Edition; June 6, 2003, Vol. 42 Issue: 22 p2462-2481, 20p
Autor:
Chubanov, Vladimir1 vladimir.chubanov@lrz.uni-muenchen.de, Schäfer, Sebastian1 sebastian.schaefer@daad-alumni.de, Ferioli, Silvia1 silvia.ferioli@lrz.uni-muenchen.de, Gudermann, Thomas1 thomas.gudermann@lrz.uni-muenchen.de
Publikováno v:
Cells (2073-4409). 2014, Vol. 3 Issue 4, p1089-1101. 13p.
Autor:
Mark R. Hutchinson, Yibo Wang, Xiaohui Wang, Hongshuang Wang, Tianshu Zhang, Hang Yin, Hongyuan Li, Shuting Zhang
Publikováno v:
Accounts of chemical research. 53(5)
Toll-like receptors (TLRs) are the "gatekeepers" of the immune system in humans and other animals to protect the host from invading bacteria, viruses, and other microorganisms. Since TLR4 was discovered as the receptor for endotoxin in the late 1990s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf6a65ad103ffe2767c475a74b4886f
https://pubmed.ncbi.nlm.nih.gov/32233400
https://pubmed.ncbi.nlm.nih.gov/32233400
Modeling and exploring human IRE1 as a strategy to design novel inhibitors: a computational approach
Autor:
Carlesso, Antonio
Inositol Requiring Enzyme 1 (IRE1) is a bifunctional serine/threonine kinase and endoribonuclease that is the major mediator of the Unfolded Protein Response (UPR) during endoplasmic reticulum (ER) stress. The association of IRE1 dysregulation with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1149::0452aafa0b34b51a92dd325c42688df5
Autor:
Wan, Jingwei, Guo, Alyssa Aihui, King, Pendelton, Guo, Shanchun, Saafir, Talib, Jiang, Yugang, Liu, Mingli
Publikováno v:
Frontiers in Pharmacology; 12/14/2020, Vol. 11, pN.PAG-N.PAG, 1p
Autor:
Thorsten Berg
Publikováno v:
ChemInform. 34
Many proteins exert their biological roles as components of complexes, and the functions of proteins are often determined by their specific interactions with other proteins. Because of the central importance of protein-protein interactions for cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5f3b3cdab457a9b598b4f9b2721a07
https://doi.org/10.1002/chin.200332269
https://doi.org/10.1002/chin.200332269