Zobrazeno 1 - 10
of 110
pro vyhledávání: '"small ORF"'
Autor:
Hua Tian, Lu Tang, Zihan Yang, Yanxi Xiang, Qi Min, Mengshuang Yin, Huili You, Zhangang Xiao, Jing Shen
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Dysregulated gene expression and imbalance of transcriptional regulation are typical features of cancer. RNA always plays a key role in these processes. Human transcripts contain many RNAs without long open reading frames (ORF, > 100 aa) and
Externí odkaz:
https://doaj.org/article/8907311b94814a668549d387a8c2fd76
Publikováno v:
Cells, Vol 13, Iss 19, p 1645 (2024)
Recently developed experimental and computational approaches to identify putative coding small ORFs (smORFs) in genomes have revealed thousands of smORFs localized within coding and non-coding RNAs. They can be translated into smORF peptides or micro
Externí odkaz:
https://doaj.org/article/1151405a033645f2863c662e983590f3
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1433-1447 (2023)
Background: Long non-coding RNA (lncRNA) is one of the most essential forms of transcripts, playing crucial regulatory roles in the development of cancers and diseases without protein-coding ability. It was assumed that short ORFs (sORFs) in lncRNA w
Externí odkaz:
https://doaj.org/article/73149bc3e97d4763a8d5af53764dfdf3
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Background Recent technological advances have revealed thousands of functional open reading frames (ORF) that have eluded reference genome annotations. These overlooked ORFs are found throughout the genome, in any reading frame of transcript
Externí odkaz:
https://doaj.org/article/9e1dd63cff7c499e851c87f91e7a2b6e
Autor:
Haruaki Kobayashi, Kazuaki Murakami, Shigeo S. Sugano, Kentaro Tamura, Yoshito Oka, Tomonao Matsushita, Tomoo Shimada
Publikováno v:
Frontiers in Plant Science, Vol 13 (2023)
In the past two decades, many plant peptides have been found to play crucial roles in various biological events by mediating cell-to-cell communications. However, a large number of small open reading frames (sORFs) or short genes capable of encoding
Externí odkaz:
https://doaj.org/article/7165d458d5cd468ba9fa182681210d7d
Autor:
Hsin-Yen Larry Wu, Polly Yingshan Hsu
Publikováno v:
Plant Methods, Vol 17, Iss 1, Pp 1-7 (2021)
Abstract Background Ribo-seq has revolutionized the study of genome-wide mRNA translation. High-quality Ribo-seq data display strong 3-nucleotide (nt) periodicity, which corresponds to translating ribosomes deciphering three nts at a time. While 3-nt
Externí odkaz:
https://doaj.org/article/70a662b799e947b3bb5a9dc3ea0dcccb
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Long non-coding RNAs (lncRNAs) are primarily recognized as non-coding transcripts longer than 200 nucleotides with low coding potential and are present in both eukaryotes and prokaryotes. Recent findings reveal that lncRNAs can code for micropeptides
Externí odkaz:
https://doaj.org/article/53a1a779cf854933a5b81ea76c12b3ea
Autor:
Jingjing Jin, Lijun Meng, Kai Chen, Yalong Xu, Peng Lu, Zhaowu Li, Jiemeng Tao, Zefeng Li, Chen Wang, Xiaonian Yang, Shizhou Yu, Zhixiao Yang, Linggai Cao, Peijian Cao
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Long non-coding RNAs (lncRNAs) regulate many biological processes in plants, including defense against pathogens and herbivores. Recently, many small ORFs embedded in lncRNAs have been identified to encode biologically functional peptides (small ORF-
Externí odkaz:
https://doaj.org/article/cac271df860b48868b491b09d0847b76
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Akademický článek
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