Zobrazeno 1 - 10
of 128
pro vyhledávání: '"smORF"'
Publikováno v:
Cells, Vol 13, Iss 19, p 1645 (2024)
Recently developed experimental and computational approaches to identify putative coding small ORFs (smORFs) in genomes have revealed thousands of smORFs localized within coding and non-coding RNAs. They can be translated into smORF peptides or micro
Externí odkaz:
https://doaj.org/article/1151405a033645f2863c662e983590f3
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 16, Iss 1, Pp 1-18 (2023)
Abstract Background Methanotrophs have emerged as promising hosts for the biological conversion of methane into value-added chemicals, including various organic acids. Understanding the mechanisms of acid tolerance is essential for improving organic
Externí odkaz:
https://doaj.org/article/d1367890d11e4446bdfe40a199bfcf14
Autor:
Si-Min Fan, Ze-Qi Li, Shi-Zhe Zhang, Liang-Yu Chen, Xi-Ying Wei, Jian Liang, Xin-Qing Zhao, Chun Su
Publikováno v:
mSystems, Vol 8, Iss 5 (2023)
ABSTRACT Small open reading frames (smORFs) are widely distributed in various living organisms. However, their functions remain largely unexplored. In addition, annotation and detection of smORFs are limited using existing methods and hindered by the
Externí odkaz:
https://doaj.org/article/a593b0db01884024a382c2902e7964a7
Autor:
Alyssa Zi-Xin Leong, Pey Yee Lee, M. Aiman Mohtar, Saiful Effendi Syafruddin, Yuh-Fen Pung, Teck Yew Low
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-15 (2022)
Abstract A short open reading frame (sORFs) constitutes ≤ 300 bases, encoding a microprotein or sORF-encoded protein (SEP) which comprises ≤ 100 amino acids. Traditionally dismissed by genome annotation pipelines as meaningless noise, sORFs were
Externí odkaz:
https://doaj.org/article/2fc1cfb9a2484c9089e323bf140597ed
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 100-113 (2022)
Abstract Recent advances in the transcriptomics, translatomics, and proteomics have led us to the exciting new world of functional endogenous microproteins. These microproteins have a small size and are derived from small open reading frames (smORFs)
Externí odkaz:
https://doaj.org/article/8c22c88f9c9c4bb8b3b7a03187c4140e
Autor:
Jose I. Pueyo, Jorge Salazar, Carolina Grincho, Jimena Berni, Benjamin P. Towler, Sarah F. Newbury
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Recent advances in proteogenomic techniques and bioinformatic pipelines have permitted the detection of thousands of translated small Open Reading Frames (smORFs), which contain less than 100 codons, in eukaryotic genomes. Hundreds of these actively
Externí odkaz:
https://doaj.org/article/be316e1f25814526bb4e696953c8b099
Autor:
Justin A Bosch, Berrak Ugur, Israel Pichardo-Casas, Jordan Rabasco, Felipe Escobedo, Zhongyuan Zuo, Ben Brown, Susan Celniker, David A Sinclair, Hugo J Bellen, Norbert Perrimon
Publikováno v:
eLife, Vol 11 (2022)
Naturally produced peptides (
Externí odkaz:
https://doaj.org/article/6549c99e7d9d4f4292fd9b2eb3a57f4b
Akademický článek
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Akademický článek
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Autor:
Azza Dib, Jennifer Zanet, Alexandra Mancheno-Ferris, Maylis Gallois, Damien Markus, Philippe Valenti, Simon Marques-Prieto, Serge Plaza, Yuji Kageyama, Hélène Chanut-Delalande, François Payre
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
There is growing evidence that peptides encoded by small open-reading frames (sORF or smORF) can fulfill various cellular functions and define a novel class regulatory molecules. To which extend transcripts encoding only smORF peptides compare with c
Externí odkaz:
https://doaj.org/article/c15ff433140443749209a5e9d834ffad