Zobrazeno 1 - 10
of 1 676
pro vyhledávání: '"slco1b1"'
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 4889-4899 (2024)
Zhikang Yu,1,2,* Zifang Shang,1,2,* Qingyan Huang,3 Heming Wu,4 Sandip Patil5,6 1Institute of Basic Medical Sciences, Meizhou People’s Hospital, Meizhou Academy of Medical Sciences, Meizhou, 514031, People’s Republic of China; 2Guangdong
Externí odkaz:
https://doaj.org/article/9d3c6652927b47ceb2395ae43a92feb3
Publikováno v:
Безопасность и риск фармакотерапии, Vol 12, Iss 2, Pp 167-177 (2024)
INTRODUCTION. The pathogenesis of antibiotic-associated drug-induced liver injury (DILI) in children has not been fully elucidated to date. Certain genotypes in patients increase the probability of developing DILI. Therefore, the identification of ph
Externí odkaz:
https://doaj.org/article/931e148f11904fb9ac2f7b9613665199
Autor:
Arooj Fatima Sheikh, Nayla Munawar, Rukhsana Nawaz, Hizbullah Khan, Mehwish Rafique, Faryal Jahan, Sagheer Ahmed
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundAngiotensin-converting enzyme inhibitors (ACEIs) are prescribed for individuals with high cardiovascular (CV) risk; however, persistent cough limits the use of ACEIs in a large number of patients. The current study aimed to identify the gen
Externí odkaz:
https://doaj.org/article/f95e36e8d82a47e5bef2d18492fbaf0c
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-8 (2024)
Abstract Background SLCO1B1 plays an important role in mediating hepatic clearance of many different drugs including statins, angiotensin-converting enzyme inhibitors, chemotherapeutic agents and antibiotics. Several variants in SLCO1B1 have been sho
Externí odkaz:
https://doaj.org/article/e20d750a15214f5695d4348aa811f689
Autor:
Angel T. Alvarado, Ana María Muñoz, Roberto O. Ybañez-Julca, Mario Pineda-Pérez, Nesquen Tasayco-Yataco, María R. Bendezú, Jorge A. García, Felipe Surco-Laos, Haydee Chávez, Doris Laos-Anchante, Aura Molina-Cabrera, Carmela Ferreyra-Paredes, Nelly Vega-Ramos, Patricia Castillo-Romero, Javier Chávez-Espinoza, Juan Panay-Centeno, Eliades Yarasca-Carlos
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 11, Iss 6, Pp 934-952 (2023)
Context: Statins reduce the risk of stroke and prevent cardiac events in people with atherosclerosis and diabetes mellitus; and could affect the proliferation, migration, and survival of cancer cells. Aims: To review the most up-to-date and availa
Externí odkaz:
https://doaj.org/article/12ed8e0b9d0d4ce0bb52d3dcbb4af5a1
Publikováno v:
Advances in Laboratory Medicine, Vol 4, Iss 4, Pp 341-352 (2023)
Statins are one of the most prescribed medications in developed countries as the treatment of choice for reducing cholesterol and preventing cardiovascular diseases. However, a large proportion of patients experience adverse drug reactions, especiall
Externí odkaz:
https://doaj.org/article/7e93bbf3bfd84a8db697442425a2112d
Publikováno v:
Advances in Laboratory Medicine, Vol 4, Iss 4, Pp 353-364 (2023)
Las estatinas son unos de los medicamentos más prescritos en los países desarrollados por ser el tratamiento de elección para reducir los niveles de colesterol ayudando así a prevenir la enfermedad cardiovascular. Sin embargo, un gran número de
Externí odkaz:
https://doaj.org/article/8caef653a5074d7cb0a36c11586f0ed0
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Background Statin-induced myopathy is reported to be associated with the solute carrier organic anion transporter family member 1B1 gene single nucleotide polymorphism, c.521 T > C. There is no epidemiologic data on this gene polymorphism in
Externí odkaz:
https://doaj.org/article/00297825604b438bae6dd70a40ab12f2
Autor:
Giosiana Bosco, Francesco Di Giacomo Barbagallo, Maurizio Di Marco, Nicoletta Miano, Sabrina Scilletta, Salvatore Spampinato, Alessio Vitale, Federica Di Bella, Maria Montalbano, Stefania Di Mauro, Agnese Filippello, Alessandra Scamporrino, Agostino Milluzzo, Antonino Di Pino, Lucia Frittitta, Francesco Purrello, Salvatore Piro, Roberto Scicali
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Background and aimsFH women are less likely to receive intensive statin treatment and to obtain a 50% reduction of LDL-C from baseline compared to men with FH. SLCO1B1 rs4149056 might influence statin therapy compliance and thus LDL-C target achievem
Externí odkaz:
https://doaj.org/article/7afd45099456420e92dab1522c0ef604
Autor:
Tamara Božina, Lana Ganoci, Ena Karačić, Livija Šimičević, Majda Vrkić-Kirhmajer, Iva Klarica-Domjanović, Tena Križ, Zrinka Sertić, Nada Božina
Publikováno v:
Annals of Human Biology, Vol 49, Iss 7-8, Pp 323-331 (2022)
Background Organic anion-transporting polypeptide 1B1 (OATP1B1) and the ATP-binding cassette subfamily G member 2, ABCG2, are important transporters involved in the transport of endogenous substrates and xenobiotics, including drugs. Genetic polymorp
Externí odkaz:
https://doaj.org/article/ba302c8799c148b68bd254980828ad93