Zobrazeno 1 - 10
of 172
pro vyhledávání: '"skin vaccination"'
Publikováno v:
Expert Review of Vaccines, Vol 0, Iss 0 (2023)
Introduction Microneedles are emerging as a promising technology for vaccine delivery, with numerous advantages over traditional needle and syringe methods. Preclinical studies have demonstrated the effectiveness of MAPs in inducing robust immune res
Externí odkaz:
https://doaj.org/article/4ecb781fea1a40208370ae0a080e5da2
Akademický článek
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Autor:
Jacob W. Coffey, Nicole M. D. van der Burg, Thippayawan Rananakomol, Hwee-Ing Ng, Germain J. P. Fernando, Mark A. F. Kendall
Publikováno v:
Advanced NanoBiomed Research, Vol 2, Iss 8, Pp n/a-n/a (2022)
Many types of microneedle (MN) arrays have been tested for delivery of vaccines to the skin. However, the effect of MN geometry/array design on antibody production is still unclear. Reports suggest that systemic immune responses may be affected by ho
Externí odkaz:
https://doaj.org/article/c1b1cfcd169e43cba45a1a892c3690cb
Akademický článek
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Autor:
Joyce, Jessica C., Carroll, Timothy D., Collins, Marcus L., Chen, Min-hsin, Fritts, Linda, Dutra, Joseph C., Rourke, Tracy L., Goodson, James L., McChesney, Michael B., Prausnitz, Mark R., Rota, Paul A.
Publikováno v:
The Journal of Infectious Diseases, 2018 Jul 01. 218(1), 124-132.
Externí odkaz:
https://www.jstor.org/stable/26495426
Autor:
Ipshita Menon, Priyal Bagwe, Keegan Braz Gomes, Lotika Bajaj, Rikhav Gala, Mohammad N. Uddin, Martin J. D’Souza, Susu M. Zughaier
Publikováno v:
Micromachines, Vol 12, Iss 4, p 435 (2021)
Transdermal vaccination route using biodegradable microneedles is a rapidly progressing field of research and applications. The fear of painful needles is one of the primary reasons most people avoid getting vaccinated. Therefore, developing an alter
Externí odkaz:
https://doaj.org/article/eb73a38aa67f4bc2b2302af91df3c5fc
Publikováno v:
Vaccines, Vol 9, Iss 4, p 320 (2021)
Vaccines are an essential component of pandemic preparedness but can be limited due to challenges in production and logistical implementation. While vaccine candidates were rapidly developed against severe acute respiratory syndrome coronavirus 2 (SA
Externí odkaz:
https://doaj.org/article/c91e7cce2fab4991a72297b1d836ebae
Autor:
Sayami Ito, Sachiko Hirobe, Takuto Kawakita, Mio Saito, Ying-Shu Quan, Fumio Kamiyama, Ken J. Ishii, Mizuho Nagao, Takao Fujisawa, Masashi Tachibana, Naoki Okada
Publikováno v:
Pharmaceutics, Vol 12, Iss 3, p 267 (2020)
Transcutaneous immunization (TCI) is easy to use, minimally invasive, and has excellent efficacy in vaccines against infections. We focused on toll-like receptor (TLR) ligands as applicable adjuvants for transcutaneous formulations and characterized
Externí odkaz:
https://doaj.org/article/6e7171d817f94744ab601fe699997f77
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Skin vaccination using biodegradable microneedle patch (MNP) technology in vaccine delivery is a promising strategy showing significant advantages over conventional flu shots. In this study, we developed an MNP encapsulating a 4M2e-tFliC fusion prote
Externí odkaz:
https://doaj.org/article/db6d468dbf404088b466f735d60f269e
Autor:
Kristina Ledl, Damien Collins, Johanna M.J. Rebel, Anne C. Moore, Ksenia Arkhipova, Norbert Stockhofe-Zurwieden, Kerstin Skovgaard, Dennis McDaid, Joanne McCaffrey, Huub F. J. Savelkoul, Sandra Vreman
Publikováno v:
Vaccine 39 (2021) 13
Vaccine, 39(13), 1857-1869
Vreman, S, Rebel, J M J, McCaffrey, J, Ledl, K, Arkhipova, K, Collins, D, McDaid, D, Savelkoul, H F J, Skovgaard, K, Moore, A C & Stockhofe-Zurwieden, N 2021, ' Early immune responses in skin and lymph node after skin delivery of Toll-like receptor agonists in neonatal and adult pigs ', Vaccine, vol. 39, no. 13, pp. 1857-1869 . https://doi.org/10.1016/j.vaccine.2021.02.028
Vaccine, 39(13), 1857-1869
Vreman, S, Rebel, J M J, McCaffrey, J, Ledl, K, Arkhipova, K, Collins, D, McDaid, D, Savelkoul, H F J, Skovgaard, K, Moore, A C & Stockhofe-Zurwieden, N 2021, ' Early immune responses in skin and lymph node after skin delivery of Toll-like receptor agonists in neonatal and adult pigs ', Vaccine, vol. 39, no. 13, pp. 1857-1869 . https://doi.org/10.1016/j.vaccine.2021.02.028
The skin is potentially an important vaccine delivery route facilitated by a high number of resident antigen presenting cells (APCs), which are known to be stimulated by different Toll-like receptor agonists (TLRa). In this study, neonatal and adult