Bicalutamide Exhibits Potential to Damage Kidney via Destroying Complex I and Affecting Mitochondrial Dynamics

Autor: Kuan-Chou Chen, Chang-Rong Chen, Chang-Yu Chen, Chiung-Chi Peng, Robert Y. Peng

Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 1; Pages: 135
Journal of Clinical Medicine, Vol 11, Iss 135, p 135 (2022)
Journal of Clinical Medicine

Bicalutamide (Bic) is an androgen deprivation therapy (ADT) for treating prostate cancer, while ADT is potentially associated with acute kidney injury. Previously, we recognized Bic induced renal mitochondria dysfunction in vitro and in vivo via the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936216cd425cdf97a448b0a387bce37a

Bicalutamide Exhibits Potential to Damage Kidney via Destroying Complex I and Affecting Mitochondrial Dynamics.

Autor: Chen KC; Graduate Institute of Clinical Medicine, School of Medicine, College of Medicine, Taipei Medical University, 250 Wu-Xing St., Sin-Yi District, Taipei 11031, Taiwan.; Department of Urology, Taipei Medical University Shuang-Ho Hospital, New Taipei City 23561, Taiwan.; TMU-Research Center of Urology and Kidney, Taipei Medical University, Taipei 11031, Taiwan., Chen CR; International Medical Doctor Program, Vita-Salute San Raffaele University, 20132 Milan, Italy., Chen CY; Program of Biomedical Sciences, College of Arts and Sciences, California Baptist University, Riverside, CA 92504, USA., Peng CC; Graduate Institute of Clinical Medicine, School of Medicine, College of Medicine, Taipei Medical University, 250 Wu-Xing St., Sin-Yi District, Taipei 11031, Taiwan., Peng RY; Department of Biotechnology, College of Medical and Health Care, Hungkuang University, No. 1018, Sec. 6, Taiwan Boulevard, Shalu District, Taichung 43302, Taiwan.

Publikováno v: Journal of clinical medicine [J Clin Med] 2021 Dec 27; Vol. 11 (1). Date of Electronic Publication: 2021 Dec 27.