Zobrazeno 1 - 10
of 633
pro vyhledávání: '"sirtuin1"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Emodin (EMO) has the effect of anti-cholestasis induced by alpha-naphthylisothiocyanate (ANIT). But its mechanism is still unclear. The farnesoid X receptor (Fxr) is the master bile acid nuclear receptor. Recent studies have reported that Si
Externí odkaz:
https://doaj.org/article/99ba29c880a7474cb170cf025f64f9c1
Autor:
Victoria V. Lipson, Fedyr G. Yaremenko, Volodymyr M. Vakula, Svitlana V. Kovalenko, Alexander V. Kyrychenko, Sergiy M. Desenko, Petro О. Borysko, Sergiy O. Zozulya
Publikováno v:
SynOpen, Vol 08, Iss 02, Pp 100-108 (2024)
Externí odkaz:
https://doaj.org/article/12eb0a35b15e4b65a764fa5b44b7b381
Autor:
Akio Kusaba, Toshiro Arai
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionThe prevalence of age-related diseases, including obesity (a lipid metabolism disorder), increases with the increase in a dog’s lifespan. Most of age-related diseases are associated with oxidative stress by excessive production of react
Externí odkaz:
https://doaj.org/article/692125ddf71e4ac189a7ed5c402de58a
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Background The present study analyzes the influence of resistance training (RT) and high-intensity interval training (HIIT) on metabolic indices and serum levels of Sirtuin1 (SIRT1) in postmenopausal women who suffer from the metabolic syndr
Externí odkaz:
https://doaj.org/article/1a78d3b39f9a466b92ae0a189233e362
Autor:
Mufei Wang, Juanjuan Zhao, Jiuxia Chen, Teng Long, Mengwei Xu, Tingting Luo, Qingya Che, Yihuai He, Delin Xu
Publikováno v:
PeerJ, Vol 12, p e17094 (2024)
Liver disease is a common and serious threat to human health. The progression of liver diseases is influenced by many physiologic processes, including oxidative stress, inflammation, bile acid metabolism, and autophagy. Various factors lead to the dy
Externí odkaz:
https://doaj.org/article/5919789ef14c4cbe9cc954c96612e5ea
Publikováno v:
پزشکی بالینی ابن سینا, Vol 30, Iss 1, Pp 21-29 (2023)
Background and Objective: Sirtuin1 is one of the important indicators involved in metabolic control, obesity prevention, and homeostasis control. This study aimed to investigate the effect of combined exercises and curcumin consumption on metabolic i
Externí odkaz:
https://doaj.org/article/45227e8dba9f455890a54736244327fc
Cardiometabolic Changes in Sirtuin1-Heterozygous Mice on High-Fat Diet and Melatonin Supplementation
Autor:
Gaia Favero, Igor Golic, Francesca Arnaboldi, Annalisa Cappella, Aleksandra Korac, Maria Monsalve, Alessandra Stacchiotti, Rita Rezzani
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 860 (2024)
A hypercaloric fatty diet predisposes an individual to metabolic syndrome and cardiovascular complications. Sirtuin1 (SIRT1) belongs to the class III histone deacetylase family and sustains anabolism, mitochondrial biogenesis, and fat distribution. E
Externí odkaz:
https://doaj.org/article/526676afb9af49e98cf08e6e84ea0e48
Autor:
Ji Hyun Seo, Somi Ryu, So Young Cheon, Seong-Jun Lee, Seong-Jun Won, Chae Dong Yim, Hyun-Jin Lee, Young-Sool Hah, Jung Je Park
Publikováno v:
Cancers, Vol 16, Iss 2, p 387 (2024)
Background: Gastric cancer, one of the leading causes of cancer-related death, is strongly associated with H. pylori infection, although other risk factors have been identified. The sirtuin (Sirt) family is involved in the tumorigenesis of gastric ca
Externí odkaz:
https://doaj.org/article/cc22e2c5061446118aeb0288254e7c16
Autor:
Jitendra Kumar, Santosh Kumar
Publikováno v:
Epigenetics, Vol 17, Iss 9, Pp 953-969 (2022)
Sirtuin1 is a nutrient-sensitive class III histone deacetylase which is a well-known regulator of organismal lifespan. It has been extensively studied for its role in metabolic regulation as well. Along with its involvement in ageing and metabolism,
Externí odkaz:
https://doaj.org/article/26afa555337d4cf7a13bb394fb97f513
Publikováno v:
Cancers, Vol 15, Iss 20, p 4908 (2023)
Melatonin displays antitumor activity in several types of malignancies; however, the best delivery route and the underlying mechanisms are still unclear. Alternative non-invasive delivery route based on transdermal administration of melatonin by cryo
Externí odkaz:
https://doaj.org/article/d388b4d4e58e418da491126d6e081c20