Zobrazeno 1 - 10
of 347
pro vyhledávání: '"sirtuin 6"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionGroup 3 innate lymphoid cells (ILC3s) are enriched in the intestinal mucosa and play important roles in host defense against infection and inflammatory diseases. Sirtuin 6 (SIRT6) is a nicotinamide adenine dinucleotide (NAD+)- dependent d
Externí odkaz:
https://doaj.org/article/e484be9ef45746c987458dcd2970b477
Autor:
Kun Liu, Hecheng Wang, Yiou Wang, Xiaoxu Zhang, Ruihu Wang, Zhaoxuan Zhang, Jian Wang, Xinran Lu, Xiaoyu Wu, Yanshuo Han
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Background The management of myocardial ischemia–reperfusion injury (MIRI) presents continuous therapeutic challenges. NAD-dependent deacetylase Sirtuin 6 (Sirt6) plays distinct roles in various disease contexts and is hence investigated f
Externí odkaz:
https://doaj.org/article/988a81de79ba485f91c6a60f30f869bc
Autor:
XIA Caixia, JIANG Xiaowen, FANG Jingzhou, DUAN Dongmei, CAI Mingjing, YANG Zhixia, ZHANG Hongying
Publikováno v:
Zhongguo linchuang yanjiu, Vol 36, Iss 12, Pp 1816-1820 (2023)
Objective To explore the expression of sirtuin 6 (Sirt6) and lipid metabolism indicators in type 2 diabetic nephropathy (T2DN), and analyze their correlation with renal function indicators and their effectiveness in predicting T2DN. Methods The data
Externí odkaz:
https://doaj.org/article/28e47fdcdd4d4724a68cfe82e291f66b
Autor:
Yu-lin Liu, Jia-yu Liu, Xin-xin Zhu, Jian-hua Wei, Shuang-ling Mi, Su-ya Liu, Xiu-liang Li, Wei-wei Zhang, Ling-li Zhao, Hua Wang, De-xiang Xu, Lan Gao
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 274, Iss , Pp 116191- (2024)
The reproduction toxicity of pubertal exposure to Microcystin-LR (MC-LR) and the underlying mechanism needs to be further investigated. In the current study, pubertal male ICR mice were intraperitoneally injected with 2 μg/kg MC-LR for four weeks. P
Externí odkaz:
https://doaj.org/article/949b3852d6e14ea88ed7e15587aebe1d
Autor:
Elena Abbotto, Caterina Miro, Francesco Piacente, Annalisa Salis, Melania Murolo, Annarita Nappi, Enrico Millo, Eleonora Russo, Elena Cichero, Laura Sturla, Alberto Del Rio, Antonio De Flora, Alessio Nencioni, Monica Dentice, Santina Bruzzone
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115326- (2023)
Sirtuin 6 (SIRT6) has a critical role in cutaneous Squamous Cell Carcinoma (cSCC): SIRT6 silencing in skin SCC cells has pro-differentiating effects and SIRT6 deletion abrogated DMBA-TPA-induced skin tumorigenesis in mice. On the other hand, SIRT6 ac
Externí odkaz:
https://doaj.org/article/487ea97481c846938c17d04b08a92400
Autor:
Mahami, Neda, Abedimanesh, Nasim, Asghari, Somayyeh, Mohammadnejad, Kosar, Eskandari, Mohammad Reza, Nejadebrahimi, Zivar, Ahangar, Hassan, Nedaei, Keivan, Fathi, Mojtaba, Noori, Ehsan, Motlagh, Behrooz
Publikováno v:
Nutrition & Food Science, 2021, Vol. 52, Issue 5, pp. 843-857.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/NFS-09-2021-0272
Akademický článek
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Autor:
Chowdhury, Kushan
Indiana University-Purdue University Indianapolis (IUPUI)
Hepatic fibrosis is a cellular repair mechanism that is initiated upon prolonged damage to the liver, resulting in an accumulation of excess extracellular matrix. This eventually leads to
Hepatic fibrosis is a cellular repair mechanism that is initiated upon prolonged damage to the liver, resulting in an accumulation of excess extracellular matrix. This eventually leads to
Externí odkaz:
https://hdl.handle.net/1805/30860
Autor:
Yingdong Zhu, Shuwei Hu, Xiaoli Pan, Raja Gopoju, Fathima N. Cassim Bawa, Liya Yin, Yanyong Xu, Yanqiao Zhang
Publikováno v:
Cells, Vol 12, Iss 15, p 2009 (2023)
Histone deacetylase Sirtuin 6 (SIRT6) regulates many biological processes. SIRT6 is known to regulate hepatic lipid metabolism and inhibit the development of nonalcoholic fatty liver disease (NAFLD). We aimed to investigate the role of hepatocyte SIR
Externí odkaz:
https://doaj.org/article/3dc9008b6e614a46af09435223a0d867
Akademický článek
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