Zobrazeno 1 - 10
of 149
pro vyhledávání: '"sirtuin 5"'
Autor:
Zihan Zheng, YiZhen Liu, Danli Chen, Jianjun Yang, Lingxuan Ren, Zhen Jin, Weirong Wang, Xuyang Liu, Jianyu He, Nanbo Zheng, Rong Lin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Background and purpose: Catalpol (CAT) has diverse pharmacological functions, including cellular homeostasis maintenance and anti-inflammatory effects. Sirtuin 5 (SIRT5) plays a considerable role in regulating cellular homeostasis in cardiac
Externí odkaz:
https://doaj.org/article/bf85e4bfc4cb46dc92da6e653ba29633
Autor:
Yacong Ji, Chongyang Li, Sicheng Wan, Zhen Dong, Chaolong Liu, Leiyang Guo, Shaomin Shi, Mingxin Ci, Minghao Xu, Qian Li, Huanrong Hu, Hongjuan Cui, Yaling Liu
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 10, Pp 101036- (2024)
Tetrandrine (TET), a natural bisbenzyl isoquinoline alkaloid extracted from Stephania tetrandra S. Moore, has diverse pharmacological effects. However, its effects on melanoma remain unclear. Cellular proliferation assays, multi-omics analyses, and x
Externí odkaz:
https://doaj.org/article/0df8afc14cc54d81bde2af4f87a5bf68
Autor:
Maoxiong Wu, Jing Tan, Zhengyu Cao, Yangwei Cai, Zhaoqi Huang, Zhiteng Chen, Wanbing He, Xiao Liu, Yuan Jiang, Qingyuan Gao, Bingqing Deng, Jingfeng Wang, Woliang Yuan, Haifeng Zhang, Yangxin Chen
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103184- (2024)
Rationale: The disruption of the balance between fatty acid (FA) uptake and oxidation (FAO) leads to cardiac lipotoxicity, serving as the driving force behind diabetic cardiomyopathy (DbCM). Sirtuin 5 (Sirt5), a lysine de-succinylase, could impact di
Externí odkaz:
https://doaj.org/article/e5d6d8b82dc24d0282db5c84be7bbf0e
Autor:
Cong Ma, Xueke Zhang, Yingying Zhang, Hongzhen Ruan, Xiaofeng Xu, Caiyun Wu, Zhiming Ding, Yunxia Cao
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32466- (2024)
Sirtuin 5 (Sirt5), a member of the Sirtuin family, is involved in various intracellular biological processes. However, the function of Sirt5 in oocyte maturation has not been clearly elucidated. In this study, we observed that Sirt5 was persistently
Externí odkaz:
https://doaj.org/article/8f03771805db4649aa2eea70b32e0e61
Publikováno v:
MedComm, Vol 4, Iss 6, Pp n/a-n/a (2023)
Abstract Stroke is a major public health concern worldwide. The lack of effective therapies heightens the need for new therapeutic agents. Previous study identified sirtuin 5 (SIRT5) as a positive regulator of microglia‐induced excessive neuroinfla
Externí odkaz:
https://doaj.org/article/42fe7eb38ecd42b8a94406cbc2eb9c4a
Autor:
Oh Kwang Kwon, In Hyuk Bang, So Young Choi, Ju Mi Jeon, Ann-Yae Na, Yan Gao, Sam Seok Cho, Sung Hwan Ki, Youngshik Choe, Jun Nyung Lee, Yun-Sok Ha, Eun Ju Bae, Tae Gyun Kwon, Byung-Hyun Park, Sangkyu Lee
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 1, Pp 177-189 (2023)
Prostate cancer (PCa) is the most commonly diagnosed genital cancer in men worldwide. Around 80% of the patients who developed advanced PCa suffered from bone metastasis, with a sharp drop in the survival rate. Despite great efforts, the detailed mec
Externí odkaz:
https://doaj.org/article/346bdad8995f42bc90e9bfaa73160110
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-24 (2023)
Abstract Background Gut fungi are increasingly recognized as important contributors to host physiology, although most studies have focused on gut bacteria. Post-translational modifications (PTMs) of proteins play vital roles in cell metabolism. Howev
Externí odkaz:
https://doaj.org/article/7b829a64ba8a40cbbf7ec43c94c0693e
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-21 (2022)
Abstract Background Microglia-induced excessive neuroinflammation plays a crucial role in the pathophysiology of multiple neurological diseases, such as ischaemic stroke. Controlling inflammatory responses is considered a promising therapeutic approa
Externí odkaz:
https://doaj.org/article/874adb783f8844efb869de09e6e7e8e4
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Akademický článek
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